PDB entry 3zya
View 3zya on RCSB PDB site
Description: Human p38 MAP Kinase in Complex with 2-amino-phenylamino- dibenzosuberone
Class: transferase
Keywords: transferase, allosteric regulation, protein kinase inhibitor, structure-activity relationship, p38 mitogen-activated protein kinases
Deposited on
2011-08-18, released
2011-12-28
The last revision prior to the SCOPe 2.05 freeze date was dated
2012-02-01, with a file datestamp of
2012-01-27.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.1725
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Mitogen-activated protein kinase 14
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3zyaa_ - Heterogens: 2A8, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3zyaA (A:)
gshmlemsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkk
lsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadln
nivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarh
tddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlkl
ilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsd
kritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld
qeemes
Sequence, based on observed residues (ATOM records): (download)
>3zyaA (A:)
shmlemsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkkl
srpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnn
ivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglatrw
yrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaell
kkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahay
faqyhdpddepvadpydqsfesrdllidewksltydevisfvpppl