PDB entry 3zsi

View 3zsi on RCSB PDB site
Description: X-ray structure of p38alpha bound to VX-745
Class: transferase
Keywords: transferase
Deposited on 2011-06-28, released 2012-06-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zsia_
  • Heterogens: 52P, BOG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zsiA (A:)
gshsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrp
fqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivk
cqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtdde
mtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrl
vgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkrit
aaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeem
es

    Sequence, based on observed residues (ATOM records): (download) 
    >3zsiA (A:)
ptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiiha
krtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnikltddhvqf
liyqilrglkyihsadiihrdlkpsnlavnedcelkildfgltrwyrapeimlnwmhynq
tvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsl
kmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqs
fesrdllidewksltydevisfvppp