PDB entry 3zrf

View 3zrf on RCSB PDB site
Description: pVHL54-213-EloB-EloC complex_apo
Class: transcription
Keywords: transcription, tumour supressor protein, chronic aneamia treatment, e3 ubiquitin ligase
Deposited on 2011-06-16, released 2012-03-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-03-28, with a file datestamp of 2012-03-23.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.22755
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcription elongation factor B polypeptide 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfa_
  • Chain 'B':
    Compound: Transcription elongation factor B polypeptide 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfb_
  • Chain 'C':
    Compound: von hippel-lindau disease tumor suppressor,
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfc_
  • Chain 'D':
    Compound: Transcription elongation factor B polypeptide 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfd_
  • Chain 'E':
    Compound: Transcription elongation factor B polypeptide 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfe_
  • Chain 'F':
    Compound: von hippel-lindau disease tumor suppressor,
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrff_
  • Chain 'G':
    Compound: Transcription elongation factor B polypeptide 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfg_
  • Chain 'H':
    Compound: Transcription elongation factor B polypeptide 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfh_
  • Chain 'I':
    Compound: von hippel-lindau disease tumor suppressor,
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfi_
  • Chain 'J':
    Compound: Transcription elongation factor B polypeptide 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfj_
  • Chain 'K':
    Compound: Transcription elongation factor B polypeptide 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfk_
  • Chain 'L':
    Compound: von hippel-lindau disease tumor suppressor,
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zrfl_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zrfA (A:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmkpqdsgssaneqavq

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfA (A:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafratfealciepfssppelpdvm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3zrfB (B:)
mmyvklissdghefivkrehaltsgtikamlsgpgqfaenetnevnfreipshvlskvcm
yftykvrytnssteipefpiapeialellmaanfldc

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfB (B:)
myvklissdghefivkrehaltsgtikamlsnevnfreipshvlskvcmyftykvrytns
steipefpiapeialellmaanfldc

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3zrfC (C:)
gshmeagrprpvlrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrih
syrghlwlfrdagthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslv
kpenyrrldivrslyedledhpnvqkdlerltqeriahqrmgd

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfC (C:)
lrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrihsyrghlwlfrda
gthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslvkpenyrrldivr
slyedledhpnvqkdlerltqe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3zrfD (D:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmkpqdsgssaneqavq

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfD (D:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafrtfealciepfssppelpd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3zrfE (E:)
mmyvklissdghefivkrehaltsgtikamlsgpgqfaenetnevnfreipshvlskvcm
yftykvrytnssteipefpiapeialellmaanfldc

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfE (E:)
myvklissdghefivkrehaltsgtikamlsgnevnfreipshvlskvcmyftykvrytn
ssteipefpiapeialellmaanfldc

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3zrfF (F:)
gshmeagrprpvlrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrih
syrghlwlfrdagthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslv
kpenyrrldivrslyedledhpnvqkdlerltqeriahqrmgd

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfF (F:)
lrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrihsyrghlwlfrda
gthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslvkpenyrrldivr
slyedledhpnvqkdlerltqe

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3zrfG (G:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmkpqdsgssaneqavq

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfG (G:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmkp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3zrfH (H:)
mmyvklissdghefivkrehaltsgtikamlsgpgqfaenetnevnfreipshvlskvcm
yftykvrytnssteipefpiapeialellmaanfldc

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfH (H:)
myvklissdghefivkrehaltsgtikamlsnevnfreipshvlskvcmyftykvrytns
steipefpiapeialellmaanfldc

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3zrfI (I:)
gshmeagrprpvlrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrih
syrghlwlfrdagthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslv
kpenyrrldivrslyedledhpnvqkdlerltqeriahqrmgd

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfI (I:)
vlrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrihsyrghlwlfrd
agthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslvkpenyrrldiv
rslyedledhpnvqkdlerltqeri

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3zrfJ (J:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmkpqdsgssaneqavq

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfJ (J:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmkp

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >3zrfK (K:)
mmyvklissdghefivkrehaltsgtikamlsgpgqfaenetnevnfreipshvlskvcm
yftykvrytnssteipefpiapeialellmaanfldc

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfK (K:)
myvklissdghefivkrehaltsgtikamlnevnfreipshvlskvcmyftykvrytnss
teipefpiapeialellmaanfldc

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3zrfL (L:)
gshmeagrprpvlrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrih
syrghlwlfrdagthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslv
kpenyrrldivrslyedledhpnvqkdlerltqeriahqrmgd

    Sequence, based on observed residues (ATOM records): (download) 
    >3zrfL (L:)
vlrsvnsrepsqvifcnrsprvvlpvwlnfdgepqpyptlppgtgrrihsyrghlwlfrd
agthdgllvnqtelfvpslnvdgqpifanitlpvytlkerclqvvrslvkpenyrrldiv
rslyedledhpnvqkdlerltqe