PDB entry 3zpt

View 3zpt on RCSB PDB site
Description: Design and Synthesis of P1-P3 Macrocyclic Tertiary Alcohol Comprising HIV-1 Protease Inhibitors
Class: hydrolase
Keywords: hydrolase, rational drug design, macrocyclic tertiary alcohol
Deposited on 2013-03-01, released 2013-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366
    • conflict (62)
    • conflict (81)
    • conflict (83)
  Domains in SCOPe 2.08: d3zpta_
• Chain 'B':
  Compound: Protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366 (0-98)
    • conflict (62)
    • conflict (81)
    • conflict (83)
  Domains in SCOPe 2.08: d3zptb_
• Heterogens: CL, M8Y, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3zptA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qipieicghkaigtvlvgptptnvigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3zptB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qipieicghkaigtvlvgptptnvigrnlltqigctlnf