PDB entry 3zn0

View 3zn0 on RCSB PDB site
Description: LSD1-CoREST in complex with PRSFAA peptide
Class: oxidoreductase/peptide
Keywords: oxidoreductase-peptide complex, demethylase, transcription factor, chromatin
Deposited on 2013-02-13, released 2013-06-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-08-28, with a file datestamp of 2013-08-23.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.22906
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific histone demethylase 1A
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60341
      • conflict (190)
    Domains in SCOPe 2.05: d3zn0a1, d3zn0a2, d3zn0a3
  • Chain 'B':
    Compound: rest corepressor 1
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3zn0b1, d3zn0b2
  • Chain 'C':
    Compound: peptide
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 3ZN0 (0-5)
  • Heterogens: FAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3zn0A (A:)
    mlsgkkaaaaaaaaaaaatgteagpgtaggsengsevaaqpaglsgpaevgpgavgertp
    rkkepprasppgglaeppgsagpqagptvvpgsatpmetgiaetpegrrtsrrkrakvey
    remdeslanlsedeyyseeernakaekekklpppppqappeeenesepeepsgqagglqd
    dssggygdgqpsgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlql
    wldnpkiqltfeatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgk
    viiigsgvsglaaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggn
    pmavvskqvnmelakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnv
    lnnkpvslgqalevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhq
    qykeasevkpprditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvy
    lssrdrqildwhfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalae
    gldiklntavrqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfv
    pplpewktsavqrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlyka
    pillalvageaagimenisddvivgrclailkgifgssavpqpketvvsrwradpwargs
    ysyvaagssgndydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglr
    eagriadqflgamytlprqatpgvpaqqspsm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3zn0A (A:)
    psgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqlt
    featlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsg
    laaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvn
    melakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgq
    alevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkp
    prditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqild
    whfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntav
    rqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsa
    vqrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvage
    aagimenisddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssg
    ndydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglreagriadqfl
    gamytl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3zn0B (B:)
    mvekgpevsgkrrgrnnaaasasaaaasaaasaacaspaataasgaaassasaaaasaaa
    apnngqnkslaaaapngnsssnsweegssgsssdeehggggmrvgpqyqavvpdfdpakl
    arrsqerdnlgmlvwspnqnlseakldeyiaiakekhgynmeqalgmlfwhkhnieksla
    dlpnftpfpdewtvedkvlfeqafsfhgktfhriqqmlpdksiaslvkfyyswkktrtkt
    svmdrharkqkrereesedeleeangnnpidievdqnkeskkevpptetvpqvkkekhst
    qaknrakrkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalk
    ekldggiepyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknf
    fvnyrrrfnidevlqeweaehgkeetngpsnqkpvkspdnsikmpeeedeapvldvryas
    as
    

    Sequence, based on observed residues (ATOM records): (download)
    >3zn0B (B:)
    rkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalkekldggi
    epyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknffvnyrrr
    fnidevlqeweae
    

  • Chain 'C':
    No sequence available.