PDB entry 3zmz

View 3zmz on RCSB PDB site
Description: LSD1-CoREST in complex with PRSFAV peptide
Class: oxidoreductase
Keywords: oxidoreductase, demethylase, transcription factor, chromatin
Deposited on 2013-02-13, released 2013-06-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-08-28, with a file datestamp of 2013-08-23.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.20848
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific histone demethylase 1A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60341
      • conflict (190)
    Domains in SCOPe 2.05: d3zmza1, d3zmza2, d3zmza3
  • Chain 'B':
    Compound: rest corepressor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3zmzb1, d3zmzb2
  • Chain 'C':
    Compound: peptide
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3ZMZ (0-5)
  • Heterogens: FAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zmzA (A:)
mlsgkkaaaaaaaaaaaatgteagpgtaggsengsevaaqpaglsgpaevgpgavgertp
rkkepprasppgglaeppgsagpqagptvvpgsatpmetgiaetpegrrtsrrkrakvey
remdeslanlsedeyyseeernakaekekklpppppqappeeenesepeepsgqagglqd
dssggygdgqpsgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlql
wldnpkiqltfeatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgk
viiigsgvsglaaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggn
pmavvskqvnmelakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnv
lnnkpvslgqalevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhq
qykeasevkpprditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvy
lssrdrqildwhfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalae
gldiklntavrqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfv
pplpewktsavqrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlyka
pillalvageaagimenisddvivgrclailkgifgssavpqpketvvsrwradpwargs
ysyvaagssgndydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglr
eagriadqflgamytlprqatpgvpaqqspsm

    Sequence, based on observed residues (ATOM records): (download) 
    >3zmzA (A:)
psgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqlt
featlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsg
laaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvn
melakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgq
alevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkp
prditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqild
whfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntav
rqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsa
vqrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvage
aagimenisddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssg
ndydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglreagriadqfl
gamytl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3zmzB (B:)
mvekgpevsgkrrgrnnaaasasaaaasaaasaacaspaataasgaaassasaaaasaaa
apnngqnkslaaaapngnsssnsweegssgsssdeehggggmrvgpqyqavvpdfdpakl
arrsqerdnlgmlvwspnqnlseakldeyiaiakekhgynmeqalgmlfwhkhnieksla
dlpnftpfpdewtvedkvlfeqafsfhgktfhriqqmlpdksiaslvkfyyswkktrtkt
svmdrharkqkrereesedeleeangnnpidievdqnkeskkevpptetvpqvkkekhst
qaknrakrkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalk
ekldggiepyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknf
fvnyrrrfnidevlqeweaehgkeetngpsnqkpvkspdnsikmpeeedeapvldvryas
as

    Sequence, based on observed residues (ATOM records): (download) 
    >3zmzB (B:)
rkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalkekldggi
epyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknffvnyrrr
fnidevlqeweae

  • Chain 'C':
    No sequence available.