PDB entry 3zms

View 3zms on RCSB PDB site
Description: LSD1-CoREST in complex with INSM1 peptide
Class: oxidoreductase/peptide
Keywords: oxidoreductase-peptide complex, demethylase, transcription factor, chromatin
Deposited on 2013-02-12, released 2013-06-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-08-28, with a file datestamp of 2013-08-23.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: 0.21525
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific histone demethylase 1A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3zmsa1, d3zmsa2, d3zmsa3
  • Chain 'B':
    Compound: rest corepressor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3zmsb1, d3zmsb2
  • Chain 'C':
    Compound: Insulinoma-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3zmsA (A:)
    mlsgkkaaaaaaaaaaaatgteagpgtaggsengsevaaqpaglsgpaevgpgavgertp
    rkkepprasppgglaeppgsagpqagptvvpgsatpmetgiaetpegrrtsrrkrakvey
    remdeslanlsedeyyseeernakaekekklpppppqappeeenesepeepsgqagglqd
    dssggygdgqpsgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlql
    wldnpkiqltfeatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgk
    viiigsgvsglaaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggn
    pmavvskqvnmelakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnv
    lnnkpvslgqalevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhq
    qykeasevkpprditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvy
    lssrdrqildwhfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalae
    gldiklntavrqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfv
    pplpewktsavqrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlyka
    pillalvageaagimenisddvivgrclailkgifgssavpqpketvvsrwradpwargs
    ysyvaagssgndydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglr
    eagriadqflgamytlprqatpgvpaqqspsm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3zmsA (A:)
    sgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqltf
    eatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsgl
    aaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvnm
    elakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgqa
    levviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkpp
    rditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqildw
    hfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntavr
    qvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsav
    qrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvagea
    agimenisddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssgn
    dydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglreagriadqflg
    amytl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3zmsB (B:)
    mvekgpevsgkrrgrnnaaasasaaaasaaasaacaspaataasgaaassasaaaasaaa
    apnngqnkslaaaapngnsssnsweegssgsssdeehggggmrvgpqyqavvpdfdpakl
    arrsqerdnlgmlvwspnqnlseakldeyiaiakekhgynmeqalgmlfwhkhnieksla
    dlpnftpfpdewtvedkvlfeqafsfhgktfhriqqmlpdksiaslvkfyyswkktrtkt
    svmdrharkqkrereesedeleeangnnpidievdqnkeskkevpptetvpqvkkekhst
    qaknrakrkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalk
    ekldggiepyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknf
    fvnyrrrfnidevlqeweaehgkeetngpsnqkpvkspdnsikmpeeedeapvldvryas
    as
    

    Sequence, based on observed residues (ATOM records): (download)
    >3zmsB (B:)
    rkppkgmflsqedveavsanataattvlrqldmelvsvkrqiqnikqtnsalkekldggi
    epyrlpeviqkcnarwtteeqllavqairkygrdfqaisdvignksvvqvknffvnyrrr
    fnidevlqeweae
    

  • Chain 'C':
    No sequence available.