PDB entry 3zml

View 3zml on RCSB PDB site
Description: Anopheles funestus glutathione-s-transferase epsilon 2 (GSTe2) protein structure from different alelles: A single amino acid change confers high level of DDT resistance and cross resistance to permethrin in a major malaria vector in Africa
Class: transferase
Keywords: transferase
Deposited on 2013-02-11, released 2014-01-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: 0.1891
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione s-transferase e2
    Species: ANOPHELES FUNESTUS [TaxId:62324]
    Database cross-references and differences (RAF-indexed):
    • Uniprot G0XSZ1 (Start-222)
      • conflict (120)
      • conflict (132)
      • conflict (155)
    Domains in SCOPe 2.07: d3zmla1, d3zmla2
  • Chain 'B':
    Compound: glutathione s-transferase e2
    Species: ANOPHELES FUNESTUS [TaxId:62324]
    Database cross-references and differences (RAF-indexed):
    • Uniprot G0XSZ1 (Start-222)
      • conflict (120)
      • conflict (132)
      • conflict (155)
    Domains in SCOPe 2.07: d3zmlb1, d3zmlb2
  • Heterogens: GSH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zmlA (A:)
shmtklvlytlhlsppcraveltakalgleleqkninllagdhltpefmklnpqhtipvl
dddgtiiteshaimiylvtkygkddtlypkdpvqqarvnaalhfesgvlfarmrfiferi
lfygksdipedrieyvqksyrlledtlkddfvagskmtiadfscistissimgvvpleqs
ehpriyewidrlkqlpyyeeanggggtdlgkfvlakkeenaka

    Sequence, based on observed residues (ATOM records): (download) 
    >3zmlA (A:)
lvlytlhlsppcraveltakalgleleqkninllagdhltpefmklnpqhtipvldddgt
iiteshaimiylvtkygkddtlypkdpvqqarvnaalhfesgvlfarmrfiferilfygk
sdipedrieyvqksyrlledtlkddfvagskmtiadfscistissimgvvpleqsehpri
yewidrlkqlpyyeeanggggtdlgkfvlakkeenaka

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3zmlB (B:)
shmtklvlytlhlsppcraveltakalgleleqkninllagdhltpefmklnpqhtipvl
dddgtiiteshaimiylvtkygkddtlypkdpvqqarvnaalhfesgvlfarmrfiferi
lfygksdipedrieyvqksyrlledtlkddfvagskmtiadfscistissimgvvpleqs
ehpriyewidrlkqlpyyeeanggggtdlgkfvlakkeenaka

    Sequence, based on observed residues (ATOM records): (download) 
    >3zmlB (B:)
klvlytlhlsppcraveltakalgleleqkninllagdhltpefmklnpqhtipvldddg
tiiteshaimiylvtkygkddtlypkdpvqqarvnaalhfesgvlfarmrfiferilfyg
ksdipedrieyvqksyrlledtlkddfvagskmtiadfscistissimgvvpleqsehpr
iyewidrlkqlpyyeeanggggtdlgkfvlakkeenaka