PDB entry 3zlw

View 3zlw on RCSB PDB site
Description: Crystal structure of MEK1 in complex with fragment 3
Class: transferase
Keywords: transferase
Deposited on 2013-02-04, released 2013-05-22
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-05-29, with a file datestamp of 2013-05-24.
Experiment type: XRAY
Resolution: 2.12 Å
R-factor: 0.198
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dual specificity mitogen-activated protein kinase kinase 1 mapk/erk kinase 1, mek 1, mek1
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q02750
      • conflict (41)
    Domains in SCOPe 2.04: d3zlwa_
  • Heterogens: MT8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3zlwA (A:)
    gleeleldeqqrkrleafltqkqkvgelkdddfekiselgaanggvvfkvshkpsglvma
    rklihleikpairnqiirelqvlhecnspyivgfygafysdgeisicmehmdggsldqvl
    kkagripeqilgkvsiavikgltylrekhkimhrdvkpsnilvnsrgeiklcdfgvsgql
    idsmansfvgtrsymsperlqgthysvqsdiwsmglslvemavgrypipppdakelelmf
    gcqvegdaaetpprprtpgrplnkfgmdsrppmaifelldyivnepppklpsgvfslefq
    dfvnkcliknpaeradlkqlmvhafikrsdaeevdfagwlcstiglnq
    

    Sequence, based on observed residues (ATOM records): (download)
    >3zlwA (A:)
    eleldeqqrkrleafltqkqkvgelkdddfekiselgaanggvvfkvshkpsglvmarkl
    ihleikpairnqiirelqvlhecnspyivgfygafysdgeisicmehmdggsldqvlkka
    gripeqilgkvsiavikgltylrekhkimhrdvkpsnilvnsrgeiklcdfgvsgqlids
    mavgtrsymsperlqgthysvqsdiwsmglslvemavgrypipppdakelelmfgcpmai
    felldyivnepppklpsgvfslefqdfvnkcliknpaeradlkqlmvhafikrsdaeevd
    fagwlcstigln