PDB entry 3zk5

View 3zk5 on RCSB PDB site
Description: PikC D50N mutant bound to the 10-DML analog with the 3-(N,N-dimethylamino)ethanoate anchoring group
Class: oxidoreductase
Keywords: oxidoreductase, monooxygenase, pikromycin biosynthesis
Deposited on 2013-01-21, released 2014-01-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: 0.20047
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 hydroxylase pikc
    Species: STREPTOMYCES VENEZUELAE [TaxId:54571]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O87605
      • engineered mutation (69)
    Domains in SCOPe 2.06: d3zk5a_
  • Chain 'B':
    Compound: cytochrome p450 hydroxylase pikc
    Species: STREPTOMYCES VENEZUELAE [TaxId:54571]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O87605
      • engineered mutation (69)
    Domains in SCOPe 2.06: d3zk5b_
  • Heterogens: HEM, Z18, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zk5A (A:)
mgsshhhhhhssglvprgshmrrtqqgttasppvldlgalgqdfaadpyptyarlraegp
ahrvrtpegnevwlvvgydraravladprfskdwrnsttplteaeaalnhnmlesdpprh
trlrklvareftmrrvellrprvqeivdglvdamlaapdgradlmeslawplpitvisel
lgvpepdraafrvwtdafvfpddpaqaqtamaemsgylsrlidskrgqdgedllsalvrt
sdedgsrltseellgmahillvaghettvnliangmyallshpdqlaalradmtlldgav
eemlryegpvesatyrfpvepvdldgtvipagdtvlvvladahrtperfpdphrfdirrd
taghlafghgihfcigaplarleariavrallercpdlaldvspgelvwypnpmirglka
lpirwrrgreagrrtg

    Sequence, based on observed residues (ATOM records): (download) 
    >3zk5A (A:)
asppvldlgalgqdfaadpyptyarlraegpahrvrtpegnevwlvvgydraravladpr
fskdwrnsttplteaeaalnhnmlesdpprhtrlrklvareftmrrvellrprvqeivdg
lvdamlaapdgradlmeslawplpitvisellgvpepdraafrvwtdafvfpddpaqaqt
amaemsgylsrlidskrgqdgedllsalvrtsdedgsrltseellgmahillvaghettv
nliangmyallshpdqlaalradmtlldgaveemlryegpvesatyrfpvepvdldgtvi
pagdtvlvvladahrtperfpdphrfdirrdtaghlafghgihfcigaplarleariavr
allercpdlaldvspgelvwypnpmirglkalpirwr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3zk5B (B:)
mgsshhhhhhssglvprgshmrrtqqgttasppvldlgalgqdfaadpyptyarlraegp
ahrvrtpegnevwlvvgydraravladprfskdwrnsttplteaeaalnhnmlesdpprh
trlrklvareftmrrvellrprvqeivdglvdamlaapdgradlmeslawplpitvisel
lgvpepdraafrvwtdafvfpddpaqaqtamaemsgylsrlidskrgqdgedllsalvrt
sdedgsrltseellgmahillvaghettvnliangmyallshpdqlaalradmtlldgav
eemlryegpvesatyrfpvepvdldgtvipagdtvlvvladahrtperfpdphrfdirrd
taghlafghgihfcigaplarleariavrallercpdlaldvspgelvwypnpmirglka
lpirwrrgreagrrtg

    Sequence, based on observed residues (ATOM records): (download) 
    >3zk5B (B:)
pvldlgalgqdfaadpyptyarlraegpahrvrtpegnevwlvvgydraravladprfsk
dwrnsttplteaeaalnhnmlesdpprhtrlrklvareftmrrvellrprvqeivdglvd
amlaapdgradlmeslawplpitvisellgvpepdraafrvwtdafvfpddpaqaqtama
emsgylsrlidskrgqdgedllsalvrtsdedgsrltseellgmahillvaghettvnli
angmyallshpdqlaalradmtlldgaveemlryegpvesatyrfpvepvdldgtvipag
dtvlvvladahrtperfpdphrfdirrdtaghlafghgihfcigaplarleariavrall
ercpdlaldvspgelvwypnpmirglkalpirwr