PDB entry 3zgd

View 3zgd on RCSB PDB site
Description: crystal structure of a KEAP1 mutant
Class: transcription
Keywords: transcription, crystal contact engineering
Deposited on 2012-12-17, released 2013-06-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-06-12, with a file datestamp of 2013-06-07.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: 0.1651
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14145 (Start-309)
      • engineered mutation (240)
      • engineered mutation (242)
    Domains in SCOPe 2.07: d3zgda_
  • Chain 'B':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14145 (Start-309)
      • engineered mutation (240)
      • engineered mutation (242)
    Domains in SCOPe 2.07: d3zgdb_
  • Heterogens: ACT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zgdA (A:)
mgsshhhhhhssglvprgshmapkvgrliytaggyfrqslsyleaynpsdgtwlrladlq
vprsglagcvvggllyavggrnnspdgntdssaldcynpmtnqwspcapmsvprnrigvg
vidghiyavggshgcihhnsveryeperdewhlvapmltrrigvgvavlnrllyavggfd
gtnrlnsaecyypernewrmitamntirsgagvcvlhnciyaaggydgqdqlnsverydv
atatwtfvapmkhrrsalgitvhqgriyvlggydghtfldsvecydpdtdtwsevtrmts
grsgvgvavt

    Sequence, based on observed residues (ATOM records): (download) 
    >3zgdA (A:)
grliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3zgdB (B:)
mgsshhhhhhssglvprgshmapkvgrliytaggyfrqslsyleaynpsdgtwlrladlq
vprsglagcvvggllyavggrnnspdgntdssaldcynpmtnqwspcapmsvprnrigvg
vidghiyavggshgcihhnsveryeperdewhlvapmltrrigvgvavlnrllyavggfd
gtnrlnsaecyypernewrmitamntirsgagvcvlhnciyaaggydgqdqlnsverydv
atatwtfvapmkhrrsalgitvhqgriyvlggydghtfldsvecydpdtdtwsevtrmts
grsgvgvavt

    Sequence, based on observed residues (ATOM records): (download) 
    >3zgdB (B:)
grliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt