PDB entry 3zbx
View 3zbx on RCSB PDB site
Description: X-ray Structure of c-Met kinase in complex with inhibitor 6-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl) quinoline.
Class: transferase
Keywords: transferase, inhibitor
Deposited on
2012-11-13, released
2013-11-27
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-11-27, with a file datestamp of
2013-11-22.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.179
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Hepatocyte growth factor receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3zbxa_ - Heterogens: 6XE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3zbxA (A:)
mvhidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcav
kslnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfi
rnethnptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardm
ydkeyysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvnt
fditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehh
hhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3zbxA (A:)
npelvqavqhvvigpsslivhfnevigrghfgcvyhgtllkkihcavkslnritdigevs
qfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdli
gfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyysvhnktg
aklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrl
lqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfi