PDB entry 3wyg
View 3wyg on RCSB PDB site
Description: Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex
Class: GTP-binding protein/GTP-binding protein inhibitor
Keywords: heat repeat, nuclear export, GTP-binding protein-GTP-binding protein inhibitor complex
Deposited on
2014-08-26, released
2014-11-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-12-10, with a file datestamp of
2014-12-05.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.177
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Gsp1p
Species: Saccharomyces cerevisiae AWRI796 [TaxId:764097]
Gene: AWRI796_3356
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3wyga_ - Chain 'C':
Compound: Exportin-1
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: CRM1, G8514, KAP124, XPO1, YGR218W
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: cAMP-dependent protein kinase inhibitor alpha
Species: Homo sapiens [TaxId:9606]
Gene: PKIA, PRKACN1
Database cross-references and differences (RAF-indexed):
- Heterogens: GTP, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3wygA (A:)
msapaangevptfklvlvgdggtgkttfvkrhltgefekkyiatigvevhplsfytnfge
ikfdvwdtaglekfgglrdgyyinaqcaiimfdvtsrityknvpnwhrdlvrvcenipiv
lcgnkvdvkerkvkaktitfhrkknlqyydisaksnynfekpflwlarklagnpqlefva
sp
Sequence, based on observed residues (ATOM records): (download)
>3wygA (A:)
vptfklvlvgdggtgkttfvkrhltgefekkyiatigvevhplsfytnfgeikfdvwdta
glekfgglrdgyyinaqcaiimfdvtsrityknvpnwhrdlvrvcenipivlcgnkvdvk
erkvkaktitfhrkknlqyydisaksnynfekpflwlarklagnpqlefv
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.