PDB entry 3wxk

View 3wxk on RCSB PDB site
Description: Crystal structure of trypanosoma brucei gambiense glycerol kinase in complex with glycerol
Class: Transferase
Keywords: trypanosoma, glycerol kinase, sugar kinase superfamily, transferase, glycosome
Deposited on 2014-08-01, released 2014-12-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: 0.193
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.07: d3wxka1, d3wxka2, d3wxka3
  • Chain 'B':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.07: d3wxkb1, d3wxkb2, d3wxkb3
  • Chain 'C':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.07: d3wxkc1, d3wxkc2, d3wxkc3
  • Chain 'D':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.07: d3wxkd1, d3wxkd2, d3wxkd3
  • Heterogens: GOL, HEZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3wxkA (A:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >3wxkA (A:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3wxkB (B:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >3wxkB (B:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3wxkC (C:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >3wxkC (C:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3wxkD (D:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >3wxkD (D:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak