PDB entry 3wti

View 3wti on RCSB PDB site
Description: Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Clothianidin
Class: signaling protein
Keywords: neonicotinoids, nicotinic acetylcholine receptor, clothianidin, acetylcholine binding, SIGNALING PROTEIN
Deposited on 2014-04-11, released 2015-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-02-04, with a file datestamp of 2015-01-30.
Experiment type: XRAY
Resolution: 2.68 Å
R-factor: 0.228
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (5-End)
      • expression tag (4)
      • engineered mutation (58)
      • see remark 999 (69)
    Domains in SCOPe 2.08: d3wtia1, d3wtia2
  • Chain 'B':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (5-End)
      • expression tag (4)
      • engineered mutation (58)
      • see remark 999 (69)
    Domains in SCOPe 2.08: d3wtib1, d3wtib2
  • Chain 'C':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (5-End)
      • expression tag (4)
      • engineered mutation (58)
      • see remark 999 (69)
    Domains in SCOPe 2.08: d3wtic1, d3wtic2
  • Chain 'D':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (5-End)
      • expression tag (3-4)
      • engineered mutation (58)
      • see remark 999 (69)
    Domains in SCOPe 2.08: d3wtid1, d3wtid2
  • Chain 'E':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (5-End)
      • expression tag (3-4)
      • engineered mutation (58)
      • see remark 999 (69)
    Domains in SCOPe 2.08: d3wtie1, d3wtie2
  • Heterogens: CT4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3wtiA (A:)
eaeaadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrt
twsdrtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlymps
irqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildv
tqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >3wtiA (A:)
adradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrttwsd
rtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirqr
fscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqkk
nsvtysccpeayedvevslnfrkkgrs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3wtiB (B:)
eaeaadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrt
twsdrtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlymps
irqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildv
tqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >3wtiB (B:)
adradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrttwsd
rtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirqr
fscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqkk
nsvtysccpeayedvevslnfrkkgrse

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3wtiC (C:)
eaeaadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrt
twsdrtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlymps
irqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildv
tqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >3wtiC (C:)
adradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrttwsd
rtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirqr
fscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqkk
nsvtysccpeayedvevslnfrkkgrs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3wtiD (D:)
eaeaadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrt
twsdrtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlymps
irqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildv
tqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >3wtiD (D:)
aadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrttws
drtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirq
rfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqk
knsvtysccpeayedvevslnfrkkgrs

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3wtiE (E:)
eaeaadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrt
twsdrtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlymps
irqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildv
tqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >3wtiE (E:)
aadradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqrttws
drtlawdsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirq
rfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqk
knsvtysccpeayedvevslnfrkkgrs