PDB entry 3wf7
View 3wf7 on RCSB PDB site
Description: Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide
Class: transferase/transferase inhibitor
Keywords: SERINE/THREONINE PROTEIN KINASE DOMAIN, TRANSFERASE, PHOSPHORYLATION, ATP-BINDING, ZINC-BINDING, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2013-07-17, released
2014-08-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2014-10-29, with a file datestamp of
2014-10-24.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.175
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ribosomal protein S6 kinase beta-1
Species: Homo sapiens [TaxId:9606]
Gene: RPS6KB1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3wf7a_ - Heterogens: ZN, FS9, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3wf7A (A:)
gsftssgsvnrgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkami
vrnakdtahtkaernileevkhpfivdliyafqtggklylileylsggelfmqleregif
medtacfylaeismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvt
htfcgtieymapeilmrsghnravdwwslgalmydmltgappftgenrkktidkilkckl
nlppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfk
pllqseedvsqfdskftrqtpvdspddst
Sequence, based on observed residues (ATOM records): (download)
>3wf7A (A:)
pekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivrnakdtahtka
ernileevkhpfivdliyafqtggklylileylsggelfmqleregifmedtacfylaei
smalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdthtfcgtieymapeil
mrsghnravdwwslgalmydmltgappftgenrkktidkilkcklnlppyltqeardllk
kllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkpllq