PDB entry 3w68

View 3w68 on RCSB PDB site
Description: Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate
Class: transport protein
Keywords: Ataxia, Vitamin E deficiency, AVED, Transfer protein, Tocopherol, Vitamin E, Disease mutation, alpha-tocopherol transfer, alpha-tocopherol, phosphatidyl inositol phosphates, TRANSPORT PROTEIN
Deposited on 2013-02-11, released 2013-05-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-01-29, with a file datestamp of 2014-01-24.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.201
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-tocopherol transfer protein
    Species: Mus musculus [TaxId:10090]
    Gene: Ttpa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3w68a1, d3w68a2
  • Chain 'B':
    Compound: alpha-tocopherol transfer protein
    Species: Mus musculus [TaxId:10090]
    Gene: Ttpa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3w68b1, d3w68b2
  • Chain 'C':
    Compound: alpha-tocopherol transfer protein
    Species: Mus musculus [TaxId:10090]
    Gene: Ttpa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3w68c1, d3w68c2
  • Chain 'D':
    Compound: alpha-tocopherol transfer protein
    Species: Mus musculus [TaxId:10090]
    Gene: Ttpa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3w68d1, d3w68d2
  • Heterogens: VIV, 4PT, PBU, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3w68A (A:)
gplgspefspllqpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmkn
yykwraecpelsadlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydv
frvslitselivqevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvr
gihlinepvifhavfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsm
edicqewtnfimksedylssisetiq

    Sequence, based on observed residues (ATOM records): (download) 
    >3w68A (A:)
qpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmknyykwraecpels
adlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydvfrvslitseliv
qevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvrgihlinepvifh
avfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsmedicqewtnfim
ksedylssise

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3w68B (B:)
gplgspefspllqpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmkn
yykwraecpelsadlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydv
frvslitselivqevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvr
gihlinepvifhavfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsm
edicqewtnfimksedylssisetiq

    Sequence, based on observed residues (ATOM records): (download) 
    >3w68B (B:)
llqpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmknyykwraecpe
lsadlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydvfrvslitsel
ivqevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvrgihlinepvi
fhavfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsmedicqewtnf
imksedylssise

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3w68C (C:)
gplgspefspllqpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmkn
yykwraecpelsadlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydv
frvslitselivqevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvr
gihlinepvifhavfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsm
edicqewtnfimksedylssisetiq

    Sequence, based on observed residues (ATOM records): (download) 
    >3w68C (C:)
pglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmknyykwraecpelsa
dlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydvfrvslitselivq
evetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvrgihlinepvifha
vfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsmedicqewtnfimk
sedylssiseti

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3w68D (D:)
gplgspefspllqpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmkn
yykwraecpelsadlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydv
frvslitselivqevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvr
gihlinepvifhavfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsm
edicqewtnfimksedylssisetiq

    Sequence, based on observed residues (ATOM records): (download) 
    >3w68D (D:)
qpglaelrrrvqeagvpqtpqpltdafllrflrardfdldlawrlmknyykwraecpels
adlrprsilgllkagyhgvlrsrdstgsrvliyriaywdpkvftaydvfrvslitseliv
qevetqrngvkaifdlegwqvshafqitpsvakkiaavltdsfplkvrgihlinepvifh
avfsmikpfltekikdrihlhgnnykssmlqhfpdilpreyggkefsmedicqewtnfim
ksedylssise