PDB entry 3vwk

View 3vwk on RCSB PDB site
Description: Ternary crystal structure of the human NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide complex
Class: immune system
Keywords: cd1d, nkt t cell receptor, alpha-galactosylceramide, protein receptor complex, cell membrane, disulfide bond, endosome, glycoprotein, host-virus interaction, immune response, immunoglobulin domain, innate immunity, lysosome, membrane, transmembrane, disease mutation, glycation, MHC I, pyrrolidone carboxylic acid, secreted, immune system
Deposited on 2012-08-24, released 2012-10-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-08-14, with a file datestamp of 2013-08-09.
Experiment type: XRAY
Resolution: 2.94 Å
R-factor: 0.194
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3vwka1, d3vwka2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3vwkb_
  • Chain 'C':
    Compound: NKT15 T cell receptor alpha-chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3VWK
    Domains in SCOPe 2.05: d3vwkc1, d3vwkc2
  • Chain 'D':
    Compound: NKT15 T cell receptor beta-chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3VWK
    Domains in SCOPe 2.05: d3vwkd1, d3vwkd2
  • Heterogens: NAG, 4GH, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vwkA (A:)
spgvpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfs
dqqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafq
gkdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgks
elkkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpna
detwylratldvvageaaglscrvkhsslegqdivlywhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3vwkA (A:)
lfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwetl
qhifrvyrssftrdvkefakmlrlsyplelqvsagcevhnnffhvafqgkdilsfqgtsw
eptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqvkpkawl
srgpspgrlllvchvsgfypkpvwvkwmtqpgdilpnadetwylratldvlscrvkhssl
egqdivlyw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vwkB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >3vwkB (B:)
qrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdws
fyllyyteftptekdeyacrvnhvtlsqpkivkwdr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3vwkC (C:)
mknqveqspqsliilegknctlqcnytvspfsnlrwykqdtgrgpvsltimtfsentksn
grytatldadtkqsslhitasqlsdsasyicvvsdrgstlgrlyfgrgtqltvwpdiqnp
dpavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavaw
snksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >3vwkC (C:)
qveqspqsliilegknctlqcnytvspfsnlrwykqdtgrgpvsltimtfsentksngry
tatldadtkqsslhitasqlsdsasyicvvsdrgstlgrlyfgrgtqltvwpdiqnpdpa
vyqlrdssvclftdfdsqtnvsqsdsdvyitdkcvldmrsmdfksnsavawsnksdfaca
nafnnsiipedtff

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3vwkD (D:)
meadiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstekgd
lssestvsrirtehfpltlesarpshtsqylcassglrdrglyeqyfgpgtrltvtedlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >3vwkD (D:)
diyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstekgdlss
estvsrirtehfpltlesarpshtsqylcassglrdrglyeqyfgpgtrltvtedlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
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