PDB entry 3vw8

View 3vw8 on RCSB PDB site
Description: Crystal structure of human c-Met kinase domain with its inhibitor
Class: transferase/transferase inhibitor
Keywords: Transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-08-08, released 2013-08-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-12-04, with a file datestamp of 2013-11-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.215
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3vw8a_
  • Heterogens: DF6, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vw8A (A:)
vqypltdmspiltsgdsdisspllqntvhidlslnpelvqavqhvvigpsslivhfnevi
grghfgcvyhgtlldndgkkihcavkslnritdigevsqfltegiimkdfshpnvlsllg
iclrsegsplvvlpymkhgdlrnfirnethnptvkdligfglqvakgmkylaskkfvhrd
laarncmldekftvkvadfglardmydkeyysvhnktgaklpvkwmaleslqtqkfttks
dvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhpka
emrpsfselvsrisaifstfigehyvhv

    Sequence, based on observed residues (ATOM records): (download) 
    >3vw8A (A:)
vqypltdmspiltsgddlslnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtll
dndgkkihcavkslnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlp
ymkhgdlrnfirnethnptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftv
kvadfglardmydkeyysaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappy
pditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehy
vhv