PDB entry 3vqb

View 3vqb on RCSB PDB site
Description: HIV-1 IN core domain in complex with 6-fluoro-4H-1,3-benzodioxine-8-carboxylic acid
Class: transferase/transferase inhibitor
Keywords: RNaseH, DNA binding, DNA cleavage, DNA integration, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-21, released 2013-01-30
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.204
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (76)
      • engineered mutation (84)
      • engineered mutation (130)
    Domains in SCOPe 2.03: d3vqba_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (76)
      • engineered mutation (130)
    Domains in SCOPe 2.03: d3vqbb_
  • Heterogens: CD, SO4, FBG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vqbA (A:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vqbA (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacdwagikqedgipsmnkelkkiigqvrdqaehlktavqmavfihnhk
rkggiggysagerivdiiatdi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vqbB (B:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vqbB (B:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacdwagikqeesmnkelkkiigqvrdqaehlktavqmavfihnhkrkg
giggysagerivdiiatdiq