PDB entry 3vq6

View 3vq6 on RCSB PDB site
Description: HIV-1 IN core domain in complex with (1-methyl-5-phenyl-1H-pyrazol-4-yl)methanol
Class: transferase/transferase inhibitor
Keywords: RNAseH, DNA binding, DNA cleavage, DNA integration, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-20, released 2013-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.208
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (1)
      • engineered mutation (76)
      • engineered mutation (84)
      • engineered mutation (130)
    Domains in SCOPe 2.07: d3vq6a_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (1)
      • engineered mutation (76)
      • engineered mutation (84)
      • engineered mutation (130)
    Domains in SCOPe 2.07: d3vq6b_
  • Heterogens: CD, BCK, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vq6A (A:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq6A (A:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedgipviesmnkelkkiigqvrdqaehlktavqmavfi
hnhkrkggiggysagerivdiiatd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vq6B (B:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq6B (B:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedgesmnkelkkiigqvrdqaehlktavqmavfihnhk
rkggiggysagerivdiiatdiq