PDB entry 3vo3
View 3vo3 on RCSB PDB site
Description: Crystal Structure of the Kinase domain of Human VEGFR2 with imidazo[1,2-b]pyridazine derivative
Class: transferase/transferase inhibitor
Keywords: vegfr2, kinase domain, Tyrosin-protein kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2012-01-19, released
2013-03-06
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-08-07, with a file datestamp of
2013-08-02.
Experiment type: XRAY
Resolution: 1.52 Å
R-factor: 0.162
AEROSPACI score: 0.65
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Vascular endothelial growth factor receptor 2
Species: Homo sapiens [TaxId:9606]
Gene: KDR, FLK1, VEGFR2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3vo3a_ - Heterogens: 0KF, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3vo3A (A:)
gamdpdelpldehcerlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcr
tvavkmlkegathsehralmselkilihighhlnvvnllgactkpggplmvivefckfgn
lstylrskrnefvpykeapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarn
illseknvvkicdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgv
llweifslgaspypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptf
selvehlgnllqanaqqd
Sequence, based on observed residues (ATOM records): (download)
>3vo3A (A:)
pldehcerlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlk
egathsehralmselkilihighhlnvvnllgactkpggplmvivefckfgnlstylrsk
rnefvpykdlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkic
dfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgasp
ypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllq
ana