PDB entry 3vj8

View 3vj8 on RCSB PDB site
Description: Crystal structure of the human squalene synthase
Class: Transferase
Keywords: Farnesyl-diphosphate farnesyltransferase, Head-to-head synthases, Cholesterol biosynthesis, Oxidoreductase, Transferase
Deposited on 2011-10-14, released 2012-04-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 1.52 Å
R-factor: 0.166
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Squalene synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: FDFT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3vj8a_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vj8A (A:)
gshmdqdslssslktcykylnqtsrsfaaviqaldgemrnavcifylvlraldtleddmt
isvekkvpllhnfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadic
rrmgigmaefldkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransm
glflqktniirdyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnal
hhipdvitylsrlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkirkgqavtlmmd
atnmpavkaiiyqymeeiyhripdsdpsssktrqiistirtqn

    Sequence, based on observed residues (ATOM records): (download) 
    >3vj8A (A:)
slssslktcykylnqtsrsfaaviqaldgemrnavcifylvlraldtleddmtisvekkv
pllhnfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadicrrmgigm
aefldkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransmglflqkt
niirdyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnalhhipdvi
tylsrlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkirkgqavtlmmdatnmpav
kaiiyqymeeiyhripdsdpsssktrqiistirtq