PDB entry 3vd1

View 3vd1 on RCSB PDB site
Description: structure of p73 DNA binding domain tetramer modulates p73 transactivation
Class: antitumor protein/DNA
Keywords: PROTEIN DNA COMPLEX, beta-immunoglobulin-like fold, TUMOUR SUPPRESSOR, ANTITUMOR PROTEIN-DNA complex
Deposited on 2012-01-04, released 2012-04-18
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-08-22, with a file datestamp of 2012-08-17.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: 0.239
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (8-11)
    Domains in SCOPe 2.04: d3vd1a_
  • Chain 'B':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (11)
    Domains in SCOPe 2.04: d3vd1b_
  • Chain 'C':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (9-11)
    Domains in SCOPe 2.04: d3vd1c_
  • Chain 'D':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (11)
    Domains in SCOPe 2.04: d3vd1d_
  • Chain 'E':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'F':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'G':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'H':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'I':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (11)
    Domains in SCOPe 2.04: d3vd1i_
  • Chain 'J':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (11)
    Domains in SCOPe 2.04: d3vd1j_
  • Chain 'K':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (8-11)
    Domains in SCOPe 2.04: d3vd1k_
  • Chain 'L':
    Compound: Tumor protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (12-209)
      • expression tag (8-11)
    Domains in SCOPe 2.04: d3vd1l_
  • Chain 'M':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'N':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'O':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Chain 'P':
    Compound: DNA (5'-d(*cp*gp*gp*gp*cp*ap*tp*gp*cp*cp*cp*g)-3')
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vd1A (A:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1A (A:)
hhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppp
pgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpv
tgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsf
egricacpgrdrkadedhyreq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vd1B (B:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1B (B:)
fipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppppgt
airampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpvtgr
qsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsfegr
icacpgrdrkadedhyreq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3vd1C (C:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1C (C:)
hefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstpppp
gtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpvt
grqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsfe
gricacpgrdrkadedhyreq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3vd1D (D:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1D (D:)
fipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppppgt
airampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpvtgr
qsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsfegr
icacpgrdrkadedhyreq

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3vd1I (I:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1I (I:)
fipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppppgt
airampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpvtgr
qsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsfegr
icacpgrdrkadedhyreq

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3vd1J (J:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1J (J:)
fipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppppgt
airampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpvtgr
qsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsfegr
icacpgrdrkadedhyreq

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >3vd1K (K:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1K (K:)
hhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppp
pgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpv
tgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsf
egricacpgrdrkadedhyreq

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3vd1L (L:)
mghhhhhhhhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiq
ikvstppppgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnl
sqyvddpvtgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdg
qvlgrrsfegricacpgrdrkadedhyreq

    Sequence, based on observed residues (ATOM records): (download) 
    >3vd1L (L:)
hhefipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppp
pgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpv
tgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsf
egricacpgrdrkadedhyreq

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.