PDB entry 3vcy

View 3vcy on RCSB PDB site
Description: Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Class: transferase/antibiotic
Keywords: MurA, fosfomycin, peptidoglycan, Amino sugar and nucleotide sugar metabolism, Peptidoglycan biosynthesis, Cytosol, TRANSFERASE-ANTIBIOTIC complex
Deposited on 2012-01-04, released 2012-04-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-09, with a file datestamp of 2012-05-04.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.202
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Vibrio fischeri [TaxId:388396]
    Gene: murA, VFMJ11_0391
    Database cross-references and differences (RAF-indexed):
    • Uniprot B5F9P4 (0-End)
      • see remark 999 (1)
    Domains in SCOPe 2.08: d3vcya_
  • Chain 'B':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Vibrio fischeri [TaxId:388396]
    Gene: murA, VFMJ11_0391
    Database cross-references and differences (RAF-indexed):
    • Uniprot B5F9P4 (0-End)
      • see remark 999 (1)
    Domains in SCOPe 2.08: d3vcyb_
  • Chain 'C':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Vibrio fischeri [TaxId:388396]
    Gene: murA, VFMJ11_0391
    Database cross-references and differences (RAF-indexed):
    • Uniprot B5F9P4 (0-End)
      • see remark 999 (1)
    Domains in SCOPe 2.08: d3vcyc_
  • Chain 'D':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Vibrio fischeri [TaxId:388396]
    Gene: murA, VFMJ11_0391
    Database cross-references and differences (RAF-indexed):
    • Uniprot B5F9P4 (0-End)
      • see remark 999 (1)
    Domains in SCOPe 2.08: d3vcyd_
  • Heterogens: FFQ, UD1, PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vcyA (A:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhsd
dllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3vcyA (A:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vcyB (B:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhsd
dllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3vcyB (B:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3vcyC (C:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhsd
dllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3vcyC (C:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3vcyD (D:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhsd
dllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3vcyD (D:)
mdkfriqgsdkplsgevtisgaknaalpilfasllaeepvevanvpklrdvdttmellkr
lgaevsrngsvhidasgvndfcapydlvktmrasiwalgplvarfgkgqvslpggcaiga
rpvdlhihgleqlgatikleegyvkaevdgrlkgahivmdkvsvgatitvmcaatlaegt
tvlenaarepeivdtanflnaigakvsgmgtdtitiegverlgggyhevvadrietgtfl
vaaavsggkivckntkahlleavlakleeagadvqtgddwisldmtgrelkavnirtaph
pafptdmqaqftllnmmakgsgiitetifenrfmhipelqrmgahaeiegntaicgdtdg
lsgaqvmatdlrasaslviagciakgetivdriyhidrgydkiedkltalganiervhs