PDB entry 3v98

View 3v98 on RCSB PDB site
Description: S663D Stable-5-LOX
Class: oxidoreductase
Keywords: Lipoxygenase, dioxygenase, OXIDOREDUCTASE
Deposited on 2011-12-23, released 2012-05-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-08-15, with a file datestamp of 2012-08-10.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: 0.167
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arachidonate 5-lipoxygenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX5, LOG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09917 (Start-690)
      • engineered mutation (33-34)
      • see remark 999 (60-61)
      • engineered mutation (92-93)
      • engineered mutation (257)
      • engineered mutation (578)
      • engineered mutation (670-672)
      • engineered mutation (680)
    Domains in SCOPe 2.06: d3v98a1, d3v98a2
  • Chain 'B':
    Compound: Arachidonate 5-lipoxygenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX5, LOG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09917 (10-690)
      • expression tag (4-10)
      • engineered mutation (33-34)
      • see remark 999 (60-61)
      • engineered mutation (92-93)
      • engineered mutation (257)
      • engineered mutation (578)
      • engineered mutation (670-672)
      • engineered mutation (680)
      • expression tag (4-10)
      • expression tag (10)
      • expression tag (10)
      • expression tag (10)
      • expression tag (10)
      • expression tag (10)
  • Heterogens: FE2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3v98A (A:)
mgsshhhhhhssglvprgshmpsytvtvatgsqehagtddyiylslvgsagcsekhlldk
gsfergavdsydvtvdeelgeiqlvriekrkygsnddwylkyitlktphgdyiefpcyrw
itgdvevvlrdgraklarddqihilkqhrrkeletrqkqyrwmewnpgfplsidakchkd
lprdiqfdsekgvdfvlnyskamenlfinrfmhmfqsswndfadfekifvkisntiserv
mnhwqedlmfgyqflnganpvlirrctelpeklpvttemvecslerqlsleqevqqgnif
ivdfelldgidanktdpctlqflaapicllyknlankivpiaiqlnqipgdenpiflpsd
akydwllakiwvrssdfhvhqtithllrthlvsevfgiamyrqlpavhpifkllvahvrf
tiaintkareqlicecglfdkanatgggghvqmvqramkdltyaslcfpeaikargmesk
edipyyfyrddgllvweairtftaevvdiyyegdqvveedpelqdfvndvyvygmrgrks
sgfpksvksreqlseyltvviftasaqhaavnfgqydwaswipnapptmrappptakgvv
tieqivdtlpdrgrscwhlgavwalsqfqenelflgmypeehfiekpvkeamarfrknle
aivsviaernenlqlpyyyldpdripnsvai

    Sequence, based on observed residues (ATOM records): (download) 
    >3v98A (A:)
sytvtvatgsqehagtddyiylslvgsagcsekhlldkgsfergavdsydvtvdeelgei
qlvriekrkygsnddwylkyitlktphgdyiefpcyrwitgdvevvlrdgraklarddqi
hilkqhrrkeletrqkqyrwmewnpgfplsidakchkdlprdiqfdsekgvdfvlnyska
menlfinrfmhmfqsswndfadfekifvkisntiservmnhwqedlmfgyqflnganpvl
irrctelpeklpvttemvecslerqlsleqevqqgnifivdfelldgidanktdpctlqf
laapicllyknlankivpiaiqlnqipgdenpiflpsdakydwllakiwvrssdfhvhqt
ithllrthlvsevfgiamyrqlpavhpifkllvahvrftiaintkareqlicecglfdka
natgggghvqmvqramkdltyaslcfpeaikargmeskedipyyfyrddgllvweairtf
taevvdiyyegdqvveedpelqdfvndvyvygmrgrkssgfpksvksreqlseyltvvif
tasaqhaavnfgqydwaswipnapptmrappptakgvvtieqivdtlpdrgrscwhlgav
walsqfqenelflgmypeehfiekpvkeamarfrknleaivsviaernenlqlpyyyldp
dripnsvai

  • Chain 'B':
    No sequence available.