PDB entry 3v92

View 3v92 on RCSB PDB site
Description: S663A Stable-5-LOX
Class: oxidoreductase
Keywords: Lipoxygenase, dioxygenase, OXIDOREDUCTASE
Deposited on 2011-12-23, released 2012-05-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-08-15, with a file datestamp of 2012-08-10.
Experiment type: XRAY
Resolution: 2.74 Å
R-factor: 0.186
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arachidonate 5-lipoxygenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX5, LOG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09917 (Start-690)
      • expression tag (5-9)
      • engineered mutation (33-34)
      • see remark 999 (60-61)
      • engineered mutation (92-93)
      • engineered mutation (257)
      • engineered mutation (578)
      • engineered mutation (670-672)
      • engineered mutation (680)
  • Chain 'B':
    Compound: Arachidonate 5-lipoxygenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX5, LOG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09917 (Start-690)
      • engineered mutation (33-34)
      • see remark 999 (60-61)
      • engineered mutation (92-93)
      • engineered mutation (257)
      • engineered mutation (578)
      • engineered mutation (670-672)
      • engineered mutation (680)
    Domains in SCOPe 2.06: d3v92b1, d3v92b2
  • Heterogens: FE2, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3v92B (B:)
mgsshhhhhhssglvprgshmpsytvtvatgsqehagtddyiylslvgsagcsekhlldk
gsfergavdsydvtvdeelgeiqlvriekrkygsnddwylkyitlktphgdyiefpcyrw
itgdvevvlrdgraklarddqihilkqhrrkeletrqkqyrwmewnpgfplsidakchkd
lprdiqfdsekgvdfvlnyskamenlfinrfmhmfqsswndfadfekifvkisntiserv
mnhwqedlmfgyqflnganpvlirrctelpeklpvttemvecslerqlsleqevqqgnif
ivdfelldgidanktdpctlqflaapicllyknlankivpiaiqlnqipgdenpiflpsd
akydwllakiwvrssdfhvhqtithllrthlvsevfgiamyrqlpavhpifkllvahvrf
tiaintkareqlicecglfdkanatgggghvqmvqramkdltyaslcfpeaikargmesk
edipyyfyrddgllvweairtftaevvdiyyegdqvveedpelqdfvndvyvygmrgrks
sgfpksvksreqlseyltvviftasaqhaavnfgqydwaswipnapptmrappptakgvv
tieqivdtlpdrgrscwhlgavwalsqfqenelflgmypeehfiekpvkeamarfrknle
aivsviaernenlqlpyyylapdripnsvai

    Sequence, based on observed residues (ATOM records): (download) 
    >3v92B (B:)
psytvtvatgsqehagtddyiylslvgsagcsekhlldkgsfergavdsydvtvdeelge
iqlvriekrkygsnddwylkyitlktphgdyiefpcyrwitgdvevvlrdgraklarddq
ihilkqhrrkeletrqkqyrwmewnpgfplsidakchkdlprdiqfdsekgvdfvlnysk
amenlfinrfmhmfqsswndfadfekifvkisntiservmnhwqedlmfgyqflnganpv
lirrctelpeklpvttemvecslerqlsleqevqqgnifivdfelldgidanktdpctlq
flaapicllyknlankivpiaiqlnqipgdenpiflpsdakydwllakiwvrssdfhvhq
tithllrthlvsevfgiamyrqlpavhpifkllvahvrftiaintkareqlicecglfdk
anatgggghvqmvqramkdltyaslcfpeaikargmeskedipyyfyrddgllvweairt
ftaevvdiyyegdqvveedpelqdfvndvyvygmrgrkssgfpksvksreqlseyltvvi
ftasaqhaavnfgqydwaswipnapptmrappptakgvvtieqivdtlpdrgrscwhlga
vwalsqfqenelflgmypeehfiekpvkeamarfrknleaivsviaernenlqlpyyyla
pdripnsvai