PDB entry 3uzq
View 3uzq on RCSB PDB site
Description: Crystal structure of the dengue virus serotype 1 envelope protein domain III in complex with the variable domains of Mab 4E11
Class: immune system
Keywords: dengue antibody neutralization, IMMUNE SYSTEM
Deposited on
2011-12-07, released
2012-02-22
The last revision prior to the SCOPe 2.03 freeze date was dated
2012-04-18, with a file datestamp of
2012-04-13.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.177
AEROSPACI score: 0.59
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: anti-dengue Mab 4E11
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3uzqa1, d3uzqa2 - Chain 'B':
Compound: envelope protein
Species: Dengue virus 1 [TaxId:11053]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3uzqb_ - Heterogens: GOL, EDO, MES, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3uzqA (A:)
evklleqsgaelvkpgasvrlsctasgfnikdtymswvkqrpeqglewigridpangdtk
ydpkfqgkatitadtssntaylhlssltsgdtavyycsrgwegfaywgqgtlvtvsaggg
gsggggsggggselvmtqtpaslavslgqratiscrasenvdrygnsfmhwyqqkagqpp
klliyrasnlesgiparfsgsgsrtdftltinpveaddvatyfcqrsnevpwtfgggtkl
eikrplehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3uzqA (A:)
klleqsgaelvkpgasvrlsctasgfnikdtymswvkqrpeqglewigridpangdtkyd
pkfqgkatitadtssntaylhlssltsgdtavyycsrgwegfaywgqgtlvtvsaggggs
gglvmtqtpaslavslgqratiscrasenvdrygnsfmhwyqqkagqppklliyrasnle
sgiparfsgsgsrtdftltinpveaddvatyfcqrsnevpwtfgggtkleikrp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3uzqB (B:)
mgmsyvmctgsfklekevaetqhgtvlvqvkyegtdapckipfstqdekgvtqngrlita
npivtdkekpvnieteppfgesyiivgagekalklswfkkgssigklehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3uzqB (B:)
yvmctgsfklekevaetqhgtvlvqvkyegtdapckipfstqdekgvtqngrlitanpiv
tdkekpvnieteppfgesyiivgagekalklswfk