PDB entry 3uuz
View 3uuz on RCSB PDB site
Description: Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor
Class: HYDROLASE/HYDROLASE inhibitor
Keywords: Trypsin-like serine protease, HYDROLASE, PROTEIN BINDING, DUODENUM, HYDROLASE-HYDROLASE inhibitor complex
Deposited on
2011-11-29, released
2012-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-12-05, with a file datestamp of
2018-11-30.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cationic trypsin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00760 (0-222)
- engineered mutation (78)
- engineered mutation (80)
- engineered mutation (151-154)
- engineered mutation (171)
- engineered mutation (204)
- engineered mutation (208)
Domains in SCOPe 2.08: d3uuza_ - Chain 'B':
Compound: cationic trypsin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00760 (0-222)
- engineered mutation (78)
- engineered mutation (80)
- engineered mutation (151-154)
- engineered mutation (171)
- engineered mutation (204)
- engineered mutation (208)
Domains in SCOPe 2.08: d3uuzb_ - Heterogens: CA, 0CB, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3uuzA (A:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsetynndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksassfiitsnmfcagyleggkdacqgdsggp
vvcsgklqgivswgsgcaqknkpgfytklcnyvswikqtiasn
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3uuzB (B:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsetynndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksassfiitsnmfcagyleggkdacqgdsggp
vvcsgklqgivswgsgcaqknkpgfytklcnyvswikqtiasn