PDB entry 3us0

View 3us0 on RCSB PDB site
Description: Structure of p63 DNA Binding Domain in Complex with a 22 Base Pair A/T Rich Response Element Containing a Two Base Pair "AT" Spacer Between Half Sites
Class: transcription activator/DNA
Keywords: B-DNA double helix, zinc binding, beta sandwich, Greek key, transcription factor, nucleus, TRANSCRIPTION ACTIVATOR-DNA complex
Deposited on 2011-11-22, released 2012-02-01
The last revision prior to the SCOPe 2.01 freeze date was dated 2012-02-01, with a file datestamp of 2012-01-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.208
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tumor protein 63
    Species: Homo sapiens [TaxId:9606]
    Gene: KET, P63, P73H, P73L, TP63, TP73L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H3D4 (6-End)
      • expression tag (5)
    Domains in SCOPe 2.01: d3us0a_
  • Chain 'B':
    Compound: Tumor protein 63
    Species: Homo sapiens [TaxId:9606]
    Gene: KET, P63, P73H, P73L, TP63, TP73L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H3D4 (6-End)
      • expression tag (3-5)
    Domains in SCOPe 2.01: d3us0b_
  • Chain 'C':
    Compound: Tumor protein 63
    Species: Homo sapiens [TaxId:9606]
    Gene: KET, P63, P73H, P73L, TP63, TP73L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H3D4 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.01: d3us0c_
  • Chain 'D':
    Compound: Tumor protein 63
    Species: Homo sapiens [TaxId:9606]
    Gene: KET, P63, P73H, P73L, TP63, TP73L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H3D4 (6-End)
      • expression tag (3-5)
    Domains in SCOPe 2.01: d3us0d_
  • Chain 'E':
    Compound: 5'-d(*ap*ap*ap*cp*ap*tp*gp*tp*tp*tp*ap*tp*ap*ap*ap*cp*ap*tp*gp*tp*tp*t)-3'
  • Chain 'F':
    Compound: 5'-d(*ap*ap*ap*cp*ap*tp*gp*tp*tp*tp*ap*tp*ap*ap*ap*cp*ap*tp*gp*tp*tp*t)-3'
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3us0A (A:)
gshmaspsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpp
pqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedp
itgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrc
fearicacpgrdrkadedsirkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3us0A (A:)
spsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpppqgav
irampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrq
svlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfeari
cacpgrdrkadedsi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3us0B (B:)
gshmaspsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpp
pqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedp
itgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrc
fearicacpgrdrkadedsirkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3us0B (B:)
maspsntdypgphsfdvsfqsatwtystelkklycqiaktcpiqikvmtpppqgaviram
pvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrqsvlv
pyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfearicacp
grdrkadedsirk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3us0C (C:)
gshmaspsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpp
pqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedp
itgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrc
fearicacpgrdrkadedsirkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3us0C (C:)
aspsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpppqga
virampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgr
qsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfear
icacpgrdrkadedsi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3us0D (D:)
gshmaspsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpp
pqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedp
itgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrc
fearicacpgrdrkadedsirkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3us0D (D:)
maspsntdypgphsfdvsfqatwtystelkklycqiaktcpiqikvmtpppqgaviramp
vykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrqsvlvp
yeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfearicacpg
rdrkadedsirk

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.