PDB entry 3uou

View 3uou on RCSB PDB site
Description: Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase
Class: HYDROLASE/Hydrolase Inhibitor
Keywords: PROTEIN-PROTEIN INTERACTION, HYDROLASE (SERINE PROTEASE), KUNITZ-TYPE INHIBITOR, HYDROLASE-Hydrolase Inhibitor complex
Deposited on 2011-11-17, released 2012-11-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-06-17, with a file datestamp of 2015-06-12.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chymotrypsin-like elastase family member 1
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3uoua_
  • Chain 'B':
    Compound: Kunitz-type proteinase inhibitor SHPI-1
    Species: Stichodactyla helianthus [TaxId:6123]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31713 (0-End)
      • engineered mutation (12)
    Domains in SCOPe 2.07: d3uoub_
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3uouA (A:)
vvggteaqrnswpsqislqyrsgsswahtcggtlirqnwvmtaahcvdreltfrvvvgeh
nlnqndgteqyvgvqkivvhpywntddvaagydiallrlaqsvtlnsyvqlgvlpragti
lannspcyitgwgltrtngqlaqtlqqaylptvdyaicssssywgstvknsmvcaggdgv
rsgcqgdsggplhclvngqyavhgvtsfvsrlgcnvtrkptvftrvsayiswinnviasn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3uouB (B:)
sicsepkkvgrclgyfprfyfdsetgkctpfiyggcggngnnfetlhqcraicra

    Sequence, based on observed residues (ATOM records): (download) 
    >3uouB (B:)
sicsepkkvgrclgyfprfyfdsetgkctpfiyggcggngnnfetlhqcraicr