PDB entry 3ums

View 3ums on RCSB PDB site
Description: Crystal structure of the G202A mutant of human G-alpha-i1
Class: cell cycle
Keywords: gtpase, g-protein, hydrolysis, hydrolase, cell cycle
Deposited on 2011-11-14, released 2012-02-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-02-08, with a file datestamp of 2012-02-03.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: 0.183
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Guanine nucleotide-binding protein G(i) subunit alpha-1
    Species: Homo sapiens [TaxId:9606]
    Gene: GNAI1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63096 (Start-353)
      • engineered mutation (201)
    Domains in SCOPe 2.07: d3umsa1, d3umsa2
  • Heterogens: GDP, SO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3umsA (A:)
mgctlsaedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheag
yseeeckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmt
aelagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvk
ttgivethftfkdlhfkmfdvagqrserkkwihcfegvtaiifcvalsdydlvlaedeem
nrmhesmklfdsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaa
ayiqcqfedlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >3umsA (A:)
saedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagyseee
ckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmtaelag
vikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvkttgiv
ethftfkdlhfkmfdvafegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnk
wftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtk
eiythftcatdtknvqfvfdavtdviiknnlkdcglf