PDB entry 3uku

View 3uku on RCSB PDB site
Description: Structure of Arp2/3 complex with bound inhibitor CK-869
Class: structural protein
Keywords: beta-propeller, STRUCTURAL PROTEIN, ACTIN NUCLEATION FACTOR
Deposited on 2011-11-09, released 2013-02-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-02-13, with a file datestamp of 2013-02-08.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.257
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: actin-like protein 3
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukua1, d3ukua2
  • Chain 'B':
    Compound: actin-like protein 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukub_
  • Chain 'C':
    Compound: Actin-related protein 2/3 complex subunit 1B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukuc_
  • Chain 'D':
    Compound: Actin-related protein 2/3 complex subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukud1, d3ukud2
  • Chain 'E':
    Compound: Actin-related protein 2/3 complex subunit 3
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukue_
  • Chain 'F':
    Compound: Actin-related protein 2/3 complex subunit 4
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukuf_
  • Chain 'G':
    Compound: Actin-related protein 2/3 complex subunit 5
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ukug_
  • Heterogens: C69, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ukuA (A:)
magrlpacvvdcgtgytklgyagntepqfiipsciaikesakvgdqaqrrvmkgvddldf
figdeaiekptyatkwpirhgivedwdlmerfmeqvifkylraepedhyflltepplntp
enreytaeimfesfnvpglyiavqavlalaaswtsrqvgertltgtvidsgdgvthvipv
aegyvigscikhipiagrdityfiqqllrdrevgippeqsletakavkerysyvcpdlvk
efnkydtdgskwikqytginaiskkefsidvgyerflgpeiffhpefanpdftqpisevv
deviqncpidvrrplyknivlsggstmfrdfgrrlqrdlkrtvdarlklseelsggrlkp
kpidvqvithhmqryavwfggsmlastpefyqvchtkkdyeeigpsicrhnpvfgvms

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuA (A:)
agrlpacvvdcgtgytklgyagntepqfiipsciaikemkgvddldffigdeaiekptya
tkwpirhgivedwdlmerfmeqvifkylraepedhyflltepplntpenreytaeimfes
fnvpglyiavqavlalaaswtsrqvgertltgtvidsgdgvthvipvaegyvigscikhi
piagrdityfiqqllrdrevgippeqsletakavkerysyvcpdlvkefnkydtdgskwi
kqytginaiskkefsidvgyerflgpeiffhpefanpdftqpisevvdeviqncpidvrr
plyknivlsggstmfrdfgrrlqrdlkrtvdarlklseelskpkpidvqvithhmqryav
wfggsmlastpefyqvchtkkdyeeigpsicrhnpvfgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ukuB (B:)
mdsqgrkvvvcdngtgfvkcgyagsnfpehifpalvgrpiirsttkvgnieikdlmvgde
aselrsmlevnypmengivrnwddmkhlwdytfgpeklnidtrnckillteppmnptknr
ekivevmfetyqfsgvyvaiqavltlyaqglltgvvvdsgdgvthicpvyegfslphltr
rldiagrditrylikllllrgyafnhsadfetvrmikeklcyvgynieqeqklalettvl
vesytlpdgriikvggerfeapealfqphlinvegvgvaellfntiqaadidtrsefykh
ivlsggstmypglpsrlerelkqlylervlkgdveklskfkiriedpprrkhmvflggav
ladimkdkdnfwmtrqeyqekgvrvleklgvtvr

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuB (B:)
gvvvdsgdgvthicpvyegfslphltrrldiagrditrylikllllrgyafnhsadfetv
rmikeklcyvgynieqeqklalettvlvesytlpdgriikvggerfeapealfqphlinv
egvgvaellfntiqaadidtrsefykhivlsggstmypglpsrlerelkqlylervlkgd
veklskfkiriedpp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3ukuC (C:)
mayhsflvepischawnkdrtqiaicpnnhevhiyeksgnkwvqvhelkehngqvtgidw
apdsnrivtcgtdrnayvwtlkgrtwkptlvilrinraarcvrwapnekkfavgsgsrvi
sicyfeqendwwvckhikkpirstvlsldwhpnsvllaagscdfkcrifsayikeveerp
aptpwgskmpfgelmfesssscgwvhgvcfsangsrvawvshdstvcladadkkmavatl
asetlpllavtfitesslvaaghdcfpvlftydsaagklsfggrldvpkqssqrgltare
rfqnldkkassegsaaagagldslhknsvsqisvlsggkakcsqfcttgmdggmsiwdvr
slesalkdlkiv

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuC (C:)
ayhsflvepischawnkdrtqiaicpnnhevhiyeksgnkwvqvhelkehngqvtgidwa
pdsnrivtcgtdrnayvwtlkgrtwkptlvilrinraarcvrwapnekkfavgsgsrvis
icyfeqendwwvckhikkpirstvlsldwhpnsvllaagscdfkcrifsayikeveerpa
ptpwgskmpfgelmfesssscgwvhgvcfsangsrvawvshdstvcladadkkmavatla
setlpllavtfitesslvaaghdcfpvlftydsaagklsfggrldvpagldslhknsvsq
isvlsggkakcsqfcttgmdggmsiwdvrslesalkdlkiv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3ukuD (D:)
millevnnriieetlalkfenaaagnkpeavevtfadfdgvlyhisnpngdktkvmvsis
lkfykelqahgadellkrvygsylvnpesgynvsllydlenlpaskdsivhqagmlkrnc
fasvfekyfqfqeegkegenravihyrddetmyveskkdrvtvvfstvfkddddvvigkv
fmqefkegrrashtapqvlfshrepplelkdtdaavgdnigyitfvlfprhtnasardnt
inlihtfrdylhyhikcskayihtrmraktsdflkvlnrarpdaekkemktitgktfssr

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuD (D:)
millevnnriieetlalkfenaaagnkpeavevtfadfdgvlyhisnpngdktkvmvsis
lkfykelqahgadellkrvygsylvnpesgynvsllydlenlpaskdsivhqagmlkrnc
fasvfekyfqfqeegkegenravihyrddetmyveskkdrvtvvfstvfkddddvvigkv
fmqefkegrrashtapqvlfshrepptdaavgdnigyitfvlfprhtnasardntinlih
tfrdylhyhikcskayihtrmraktsdflkvlnrarp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3ukuE (E:)
mpayhsslmdpdtklignmallpirsqfkgpapretkdtdivdeaiyyfkanvffknyei
kneadrtliyitlyiseclkklqkcnsksqgekemytlgitnfpipgepgfplnaiyakp
ankqedevmraylqqlrqetglrlcekvfdpqndkpskwwtcfvkrqfmnkslsgpgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuE (E:)
payhsslmdpdtklignmallpirsqfkgpapretkdtdivdeaiyyfkanvffknyeik
neadrtliyitlyiseclkklqkcnsksqgekemytlgitnfpipgepgfplnaiyakpa
nkqedevmraylqqlrqetglrlcekvfdpqndkpskwwtcfvkrqfmnksls

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3ukuF (F:)
mtatlrpylsavratlqaalclenfssqvverhnkpevevrsskelllqpvtisrnekek
vliegsinsvrvsiavkqadeiekilchkfmrfmmmraenffilrrkpvegydisflitn
fhteqmykhklvdfvihfmeeidkeisemklsvnararivaeeflknf

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuF (F:)
atlrpylsavratlqaalclenfssqvverhnkpevevrsskelllqpvtisrnekekvl
iegsinsvrvsiavkqadeiekilchkfmrfmmmraenffilrrkpvegydisflitnfh
teqmykhklvdfvihfmeeidkeisemklsvnararivaeeflknf

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3ukuG (G:)
mskntvssarfrkvdvgeydenkfvdeedggdgqagpdegevdsclrqgnmtaalqaalk
nppintksqavkdragsivlkvlisfkandiekavqsldkngvdllmkyiykgfespsdn
ssavllqwhekalaaggvgsivrvltarktv

    Sequence, based on observed residues (ATOM records): (download) 
    >3ukuG (G:)
sarfrkvdvgeydenkfvdeedagpdegevdsclrqgnmtaalqaalknppintksqavk
dragsivlkvlisfkandiekavqsldkngvdllmkyiykgfespsdssavllqwhekal
aaggvgsivrvltarktv