PDB entry 3uiu

View 3uiu on RCSB PDB site
Description: Crystal structure of Apo-PKR kinase domain
Class: transferase
Keywords: kinase domain, TRANSFERASE
Deposited on 2011-11-06, released 2012-11-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-11-07, with a file datestamp of 2012-11-02.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.247
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interferon-induced, double-stranded RNA-activated protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF2AK2, PKR, PRKR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19525 (0-End)
      • see remark 999 (42)
    Domains in SCOPe 2.08: d3uiua_
  • Chain 'B':
    Compound: Interferon-induced, double-stranded RNA-activated protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF2AK2, PKR, PRKR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19525 (0-End)
      • see remark 999 (42)
    Domains in SCOPe 2.08: d3uiub_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3uiuA (A:)
etkytvdkrfgmdfkeieligsggfgqvfkakhridgktyvirrvkynnekaerevkala
kldhvnivhyngcwdgfdydpetsddslessdydpensknssrsktkclfiqmefcdkgt
leqwiekrrgekldkvlalelfeqitkgvdyihskklihrdlkpsniflvdtkqvkigdf
glvtslkndgkrtrskgtlrymspeqissqdygkevdlyalglilaellhvcdtafetsk
fftdlrdgiisdifdkkektllqkllskkpedrpntseilrtltvwkkspeknerhtcvl
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3uiuA (A:)
etkytvdkrfgmdfkeieligsggfgqvfkakhridgktyvirrvkynnekaerevkala
kldhvnivhyngcwdgfdydpetsrsktkclfiqmefcdkgtleqwiekrrgekldkvla
lelfeqitkgvdyihskklihrdlkpsniflvdtkqvkigdfglvtsltlrymspeqiyg
kevdlyalglilaellhvcdtafetskfftdlrdgiisdifdkkektllqkllskkpedr
pntseilrtltvwkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3uiuB (B:)
etkytvdkrfgmdfkeieligsggfgqvfkakhridgktyvirrvkynnekaerevkala
kldhvnivhyngcwdgfdydpetsddslessdydpensknssrsktkclfiqmefcdkgt
leqwiekrrgekldkvlalelfeqitkgvdyihskklihrdlkpsniflvdtkqvkigdf
glvtslkndgkrtrskgtlrymspeqissqdygkevdlyalglilaellhvcdtafetsk
fftdlrdgiisdifdkkektllqkllskkpedrpntseilrtltvwkkspeknerhtcvl
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3uiuB (B:)
etkytvdkrfgmdfkeieligsggfgqvfkakhridgktyvirrvkynnekaerevkala
kldhvnivhyngcwdgfdydpetsrsktkclfiqmefcdkgtleqwiekrrgekldkvla
lelfeqitkgvdyihskklihrdlkpsniflvdtkqvkigdfglvtsltlrymspeqiyg
kevdlyalglilaellhvcdtafetskfftdlrdgiisdifdkkektllqkllskkpedr
pntseilrtltvwkk