PDB entry 3u8h

View 3u8h on RCSB PDB site
Description: Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Class: hydrolase
Keywords: secreted phospholipase A2, phospholipase A2 activity, HYDROLASE
Deposited on 2011-10-17, released 2012-10-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-06-12, with a file datestamp of 2013-06-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.194
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phospholipase A2, membrane associated
    Species: Homo sapiens [TaxId:9606]
    Gene: PLA2G2A, PLA2B, PLA2L, RASF-A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3u8ha_
  • Chain 'B':
    Compound: Phospholipase A2, membrane associated
    Species: Homo sapiens [TaxId:9606]
    Gene: PLA2G2A, PLA2B, PLA2L, RASF-A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3u8hb_
  • Heterogens: BHP, CA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3u8hA (A:)
    nlvnfhrmiklttgkeaalsygfygchcgvggrgspkdatdrccvthdccykrlekrgcg
    tkflsykfsnsgsritcakqdscrsqlcecdkaaatcfarnkttynkkyqyysnkhcrgs
    tprc
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3u8hB (B:)
    nlvnfhrmiklttgkeaalsygfygchcgvggrgspkdatdrccvthdccykrlekrgcg
    tkflsykfsnsgsritcakqdscrsqlcecdkaaatcfarnkttynkkyqyysnkhcrgs
    tprc