PDB entry 3u73

View 3u73 on RCSB PDB site
Description: Crystal structure of stabilized human uPAR mutant in complex with ATF
Class: hydrolase/hydrolase receptor
Keywords: glycosylation, HYDROLASE-HYDROLASE RECEPTOR complex
Deposited on 2011-10-13, released 2012-04-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-04-18, with a file datestamp of 2012-04-13.
Experiment type: XRAY
Resolution: 3.19 Å
R-factor: 0.218
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: urokinase-type plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Gene: PLAU
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3u73a1, d3u73a2
  • Chain 'U':
    Compound: Urokinase plasminogen activator surface receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MO3, PLAUR, UPAR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03405 (0-End)
      • engineered mutation (46)
      • engineered mutation (258)
    Domains in SCOPe 2.07: d3u73u1, d3u73u2, d3u73u3
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3u73A (A:)
snelhqvpsncdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfyrg
kastdtmgrpclpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvglk
plvqecmvhdca

    Sequence, based on observed residues (ATOM records): (download) 
    >3u73A (A:)
ncdclnggtcvsnkyfsnihwcncpkkfggqhceidksktcyegnghfyrgkastdtmgr
pclpwnsatvlqqtyhahrsdalqlglgkhnycrnpdnrrrpwcyvqvglkplvqecmvh
dca

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >3u73U (U:)
lrcmqcktngdcrveecalgqdlcrttivrlweegeelelveksctcsektnrtlsyrtg
lkitsltevvcgldlcnqgnsgravtysrsryleciscgssdmscergrhqslqcrspee
qcldvvthwiqegeegrpkddrhlrgcgylpgcpgsngfhnndtfhflkccnttkcnegp
ilelenlpqngrqcysckgnsthgcsseetflidcrgpmnqclvatgthepknqsymvrg
catasmcqhahlgdafsmchidvscctksgcnhpdldvqyrsg

    Sequence, based on observed residues (ATOM records): (download) 
    >3u73U (U:)
lrcmqcktngdcrveecalgqdlcrttivrlweegeelelveksctcsektnrtlsyrtg
lkitsltevvcgldlcnqgnyleciscgssdmscergrhqslqcrspeeqcldvvthwiq
egeegrpkddrhlrgcgylpgcpgsngfhnndtfhflkccnttkcnegpilelenlpqng
rqcysckgnsthgcsseetflidcrgpmnqclvatgthepknqsymvrgcatasmcqhah
lgdafsmchidvscctksgcnhpdldvqy