PDB entry 3u6f

View 3u6f on RCSB PDB site
Description: Mouse TREX1 D200N mutant
Class: hydrolase/DNA
Keywords: RNase H fold, 3' exonuclease, HYDROLASE-DNA complex
Deposited on 2011-10-12, released 2011-12-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-04-18, with a file datestamp of 2012-04-13.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.223
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Three prime repair exonuclease 1
    Species: Mus musculus [TaxId:10090]
    Gene: Trex1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91XB0
      • engineered mutation (199)
    Domains in SCOPe 2.07: d3u6fa_
  • Chain 'B':
    Compound: Three prime repair exonuclease 1
    Species: Mus musculus [TaxId:10090]
    Gene: Trex1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91XB0
      • engineered mutation (199)
    Domains in SCOPe 2.07: d3u6fb_
  • Chain 'C':
    Compound: 5'-d(*gp*ap*cp*g)-3'
  • Chain 'D':
    Compound: 5'-d(*gp*ap*cp*g)-3'
  • Heterogens: BU1, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3u6fA (A:)
mgsqtlphghmqtlifldleatglpssrpevtelcllavhrralentsisqghpppvprp
prvvdklslciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcc
lvahngdrydfpllqtelarlstpspldgtfcvdsiaalkaleqasspsgngsrksyslg
siytrlywqaptdshtaegnvltllsicqwkpqallqwvdeharpfstvkpmygtpattg
ttnlrphaatattplatangspsngrsrrpkspppekvpeapsqegllaplslltlltla
iatlyglflaspgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3u6fA (A:)
phghmqtlifldleatglpssrpevtelcllavhrralensqghpppvprpprvvdklsl
ciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcclvahngdry
dfpllqtelarlstpspldgtfcvdsiaalkaleqarksyslgsiytrlywqaptdshta
egnvltllsicqwkpqallqwvdeharpfstvkpmyg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3u6fB (B:)
mgsqtlphghmqtlifldleatglpssrpevtelcllavhrralentsisqghpppvprp
prvvdklslciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcc
lvahngdrydfpllqtelarlstpspldgtfcvdsiaalkaleqasspsgngsrksyslg
siytrlywqaptdshtaegnvltllsicqwkpqallqwvdeharpfstvkpmygtpattg
ttnlrphaatattplatangspsngrsrrpkspppekvpeapsqegllaplslltlltla
iatlyglflaspgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3u6fB (B:)
phghmqtlifldleatglpssrpevtelcllavhrralisqghpppvprpprvvdklslc
iapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcclvahngdryd
fpllqtelarlstpspldgtfcvdsiaalkaleqasksyslgsiytrlywqaptdshtae
gnvltllsicqwkpqallqwvdeharpfstvkpmygtp

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.