PDB entry 3u5j

View 3u5j on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with Alprazolam
Class: signaling protein/inhibitor
Keywords: Bromodomain-containing protein 4 isoform long, BRD4, Bromodomain containing protein 4, CAP, HUNK1, MCAP, Mitotic chromosome associated protein, Structural Genomics Consortium, SGC, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2011-10-11, released 2011-11-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-03-21, with a file datestamp of 2012-03-16.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.148
AEROSPACI score: 0.65 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (0-126)
    • cloning artifact (1)
  Domains in SCOPe 2.05: d3u5ja_
• Heterogens: 08H, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3u5jA (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee