PDB entry 3u11

View 3u11 on RCSB PDB site
Description: Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Class: transport protein
Keywords: transport protein
Deposited on 2011-09-29, released 2011-10-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.197
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Species: Homo sapiens [TaxId:9606]
    Gene: HCN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3u11a_
  • Chain 'B':
    Compound: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Species: Homo sapiens [TaxId:9606]
    Gene: HCN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3u11b_
  • Heterogens: CMP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3u11A (A:)
    qgpsspmdssrrqyqekykqveqymsfhklppdtrqrihdyyehryqgkmfdeesilgel
    seplreeiinfncrklvasmplfanadpnfvtsmltklrfevfqpgdyiiregtigkkmy
    fiqhgvvsvltkgnketkladgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevl
    eeypmmrrafetvaldrldrigkknsillh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3u11A (A:)
    dssrrqyqekykqveqymsfhklppdtrqrihdyyehryqgkmfdeesilgelseplree
    iinfncrklvasmplfanadpnfvtsmltklrfevfqpgdyiiregtigkkmyfiqhgvv
    svltkgnketkladgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevleeypmmr
    rafetvaldrldrigkkn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3u11B (B:)
    qgpsspmdssrrqyqekykqveqymsfhklppdtrqrihdyyehryqgkmfdeesilgel
    seplreeiinfncrklvasmplfanadpnfvtsmltklrfevfqpgdyiiregtigkkmy
    fiqhgvvsvltkgnketkladgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevl
    eeypmmrrafetvaldrldrigkknsillh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3u11B (B:)
    dssrrqyqekykqveqymsfhklppdtrqrihdyyehryqgkmfdeesilgelseplree
    iinfncrklvasmplfanadpnfvtsmltklrfevfqpgdyiiregtigkkmyfiqhgvv
    svltkgnketkladgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevleeypmmr
    rafetvaldrldrigkknsill