PDB entry 3tzv

View 3tzv on RCSB PDB site
Description: Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine
Class: immune system
Keywords: Immunoglobulin-like, MHC class I-like, Antigen recognition, CD1d, Cell surface, IMMUNE SYSTEM
Deposited on 2011-09-27, released 2012-04-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-04-25, with a file datestamp of 2012-04-20.
Experiment type: XRAY
Resolution: 3.06 Å
R-factor: 0.239
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Invariant Natural Killer T Cell Receptor chain A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TZV
    Domains in SCOPe 2.06: d3tzva1, d3tzva2
  • Chain 'B':
    Compound: Invariant Natural Killer T Cell Receptor chain B
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TZV
    Domains in SCOPe 2.06: d3tzvb1, d3tzvb2
  • Chain 'C':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15813 (Start-275)
      • engineered mutation (40)
      • engineered mutation (106)
      • engineered mutation (161)
    Domains in SCOPe 2.06: d3tzvc1, d3tzvc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tzvd_
  • Chain 'G':
    Compound: Invariant Natural Killer T Cell Receptor chain A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TZV
    Domains in SCOPe 2.06: d3tzvg1, d3tzvg2
  • Chain 'H':
    Compound: Invariant Natural Killer T Cell Receptor chain B
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TZV
    Domains in SCOPe 2.06: d3tzvh1, d3tzvh2
  • Heterogens: LSC, HEX, D12, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tzvA (A:)
mgknqveqspqsliilegknctlqcnytvspfsnlrwykqdtgrgpvsltimtfsentks
ngrytatldadtkqsslhitasqlsdsasyicvvsdrgstlgrlyfgrgtqltvwpdiqn
pdpavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsava
wsnksdfacanafnnsiipedtffpspessale

    Sequence, based on observed residues (ATOM records): (download) 
    >3tzvA (A:)
nqveqspqsliilegknctlqcnytvspfsnlrwykqdtgrgpvsltimtfsentksngr
ytatldadtkqsslhitasqlsdsasyicvvsdrtlgrlyfgrgtqltvwpdiqnpdpav
yqlrdsksksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
acanafnnsiipedtf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tzvB (B:)
mseadiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstekg
dlssestvsrirtehfpltlesarpshtsqylcasseegalkesvgtqyfgpgtrllvle
dlknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpq
plkeqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqiv
saeawgradsvdklaaale

    Sequence, based on observed residues (ATOM records): (download) 
    >3tzvB (B:)
adiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvstekgdsse
stvsrirtehfpltlesarpshtsqylcasseegtqyfgpgtrllvledlknvfppevav
fepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpalndsr
yalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgra

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3tzvC (C:)
pvpqrlfplrclqissfansswtrtdglawlgelqthswsqdsdtvrslkpwsqgtfsdq
qwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgqasnnffhvafqgk
dilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllqgtcpqfvsgllesgksel
kkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnade
twylratldvvageaaglscrvkhsslegqdivlyw

    Sequence, based on observed residues (ATOM records): (download) 
    >3tzvC (C:)
fplrclqissfansswtrtdglawlgelqthswsqdsdtvrslkpwsqgtfsdqqwetlq
hifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgqasnnffhvafqgkdilsfq
gtsweptqeaplwvnlaiqvlnqdkwtretvqwllqgtcpqfvsgllesgkselkkqvkp
kawlsrgpsplllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwylratldv
vaaglscrvkhsslegqdivlyw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3tzvD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >3tzvD (D:)
qrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdws
fyllyyteftptedeyacrvnhvtlsqpkivkwdr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3tzvG (G:)
mgknqveqspqsliilegknctlqcnytvspfsnlrwykqdtgrgpvsltimtfsentks
ngrytatldadtkqsslhitasqlsdsasyicvvsdrgstlgrlyfgrgtqltvwpdiqn
pdpavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsava
wsnksdfacanafnnsiipedtffpspessale

    Sequence, based on observed residues (ATOM records): (download) 
    >3tzvG (G:)
nqveqspqsliilegknctlqcnytvspfsnlrwykqdtgrgpvsltimtfsentksngr
ytatldadtkqsslhitasqlsdsasyicvvsdrgstlgrlyfgrgtqltvwpdiqnpdp
avyqlrdskssdksvclftdfdsqtnvsqkdsdvyitdkcvldmrsmdfksnsavawsnk
dfacanafnnsiipedtffps

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3tzvH (H:)
mseadiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstekg
dlssestvsrirtehfpltlesarpshtsqylcasseegalkesvgtqyfgpgtrllvle
dlknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpq
plkeqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqiv
saeawgradsvdklaaale

    Sequence, based on observed residues (ATOM records): (download) 
    >3tzvH (H:)
adiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstekglss
estvsrirtehfpltlesarpshtsqylcasseegalkesvgtqyfgpgtrllvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgra