PDB entry 3txo
View 3txo on RCSB PDB site
Description: PKC eta kinase in complex with a naphthyridine
Class: transferase/transferase inhibitor
Keywords: kinase, phosphotransferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2011-09-23, released
2011-11-30
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-12-07, with a file datestamp of
2011-12-02.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.196
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Protein kinase C eta type
Species: Homo sapiens [TaxId:9606]
Gene: PRKCH, PKCL, PRKCL
Database cross-references and differences (RAF-indexed):
- Uniprot P24723
- engineered mutation (344)
Domains in SCOPe 2.05: d3txoa_ - Heterogens: 07U, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3txoA (A:)
gpkesskegngigvnssnrlgidnfefirvlgkgsfgkvmlarvketgdlyavkvlkkdv
ilqdddvectmtekrilslarnhpfltqlfccfqtpdrlffvmefvnggdlmfhiqksrr
fdeararfyaaeiisalmflhdkgiiyrdlkldnvlldheghckladfgmckegicngvt
tatfcgtpdyiapeilqemlygpavdwwamgvllyemlcghapfeaeneddlfeailnde
vvyptwlhedatgilksfmtknptmrlgsltqggehailrhpffkeidwaqlnhrqiepp
frpriksredvsnfdpdfikeepvltpideghlpminqdefrnfeyvspelqp
Sequence, based on observed residues (ATOM records): (download)
>3txoA (A:)
dnfefirvlgkgsfgkvmlarvketgdlyavkvlkkdvilqdddvectmtekrilslarn
hpfltqlfccfqtpdrlffvmefvnggdlmfhiqksrrfdeararfyaaeiisalmflhd
kgiiyrdlkldnvlldheghckladfgmckegicgtpdyiapeilqemlygpavdwwamg
vllyemlcghapfeaeneddlfeailndevvyptwlhedatgilksfmtknptmrlgslt
qggehailrhpffkeidwaqlnhrqieppfrpriksredvsnfdpdfikeepvltpideg
hlpminqdefrnfeyvsp