PDB entry 3tws

View 3tws on RCSB PDB site
Description: Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human TERF1 (chimeric peptide)
Class: signaling protein/peptide
Keywords: ankyrin repeat, protein-protein interaction, substrate recruitment, poly(ADP-ribosyl)ation, SIGNALING PROTEIN-PEPTIDE complex
Deposited on 2011-09-22, released 2011-12-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-12-28, with a file datestamp of 2011-12-23.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.18
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP5B, TANK2, TNKL, TNKS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3twsa_
  • Chain 'B':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP5B, TANK2, TNKL, TNKS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3twsb_
  • Chain 'C':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP5B, TANK2, TNKL, TNKS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3twsc_
  • Chain 'D':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP5B, TANK2, TNKL, TNKS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3twsd_
  • Chain 'E':
    Compound: human TERF1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TWS (Start-15)
  • Chain 'F':
    Compound: human TERF1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TWS (Start-15)
  • Chain 'G':
    Compound: human TERF1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TWS (Start-15)
  • Chain 'H':
    Compound: human TERF1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TWS (Start-15)
  • Heterogens: PE8, EDO, SO4, P6G, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3twsA (A:)
gamgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvvey
llqhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgk
yeicklllqhgadptkknrdgntpldlvkdgdtdiqdllrgdaal

    Sequence, based on observed residues (ATOM records): (download) 
    >3twsA (A:)
seadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvveyllqhg
advhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgkyeick
lllqhgadptkknrdgntpldlvkdgdtdiqdllrgd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3twsB (B:)
gamgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvvey
llqhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgk
yeicklllqhgadptkknrdgntpldlvkdgdtdiqdllrgdaal

    Sequence, based on observed residues (ATOM records): (download) 
    >3twsB (B:)
gnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvveyllq
hgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgkyei
cklllqhgadptkknrdgntpldlvkdgdtdiqdllr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3twsC (C:)
gamgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvvey
llqhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgk
yeicklllqhgadptkknrdgntpldlvkdgdtdiqdllrgdaal

    Sequence, based on observed residues (ATOM records): (download) 
    >3twsC (C:)
seadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvveyllqhg
advhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgkyeick
lllqhgadptkknrdgntpldlvkdgdtdiqdllrg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3twsD (D:)
gamgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvvey
llqhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgk
yeicklllqhgadptkknrdgntpldlvkdgdtdiqdllrgdaal

    Sequence, based on observed residues (ATOM records): (download) 
    >3twsD (D:)
seadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvveyllqhg
advhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgkyeick
lllqhgadptkknrdgntpldlvkdgdtdiqdllr

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.