SCOPe 2.08: Structural Classification of Proteins

PDB entry 3tvu

View 3tvu on RCSB PDB site
Description: Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 3
Class: ligase
Keywords: carboxyltransferase, ligase
Deposited on 2011-09-20, released 2011-10-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: acetyl-coa carboxylase
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: ACC1, ABP2, FAS3, MTR7, YNR016C, N3175
Database cross-references and differences (RAF-indexed):
- Uniprot Q00955
  - engineered mutation (287)
  - engineered mutation (289)
  - engineered mutation (292)
  - engineered mutation (446-447)
  - engineered mutation (452)
  - engineered mutation (555)
  - engineered mutation (557)
  - engineered mutation (559)
Domains in SCOPe 2.08: d3tvua1, d3tvua2
Chain 'B':
Compound: acetyl-coa carboxylase
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: ACC1, ABP2, FAS3, MTR7, YNR016C, N3175
Database cross-references and differences (RAF-indexed):
- Uniprot Q00955
  - engineered mutation (287)
  - engineered mutation (289)
  - engineered mutation (292)
  - engineered mutation (446-447)
  - engineered mutation (452)
  - engineered mutation (555)
  - engineered mutation (557)
  - engineered mutation (559)
Domains in SCOPe 2.08: d3tvub1, d3tvub2
Chain 'C':
Compound: acetyl-coa carboxylase
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: ACC1, ABP2, FAS3, MTR7, YNR016C, N3175
Database cross-references and differences (RAF-indexed):
- Uniprot Q00955
  - engineered mutation (287)
  - engineered mutation (289)
  - engineered mutation (292)
  - engineered mutation (446-447)
  - engineered mutation (452)
  - engineered mutation (555)
  - engineered mutation (557)
  - engineered mutation (559)
Domains in SCOPe 2.08: d3tvuc1, d3tvuc2
Heterogens: B37, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3tvuA (A:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepegtveikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3tvuA (A:)
lrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffis
neliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpq
edeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylylt
segmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsray
hdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevytsnlqlgg
tqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptnde
tydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtv
enlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilanwrgfsgg
qrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvn
aragvlepegtveikfrreklldtmnrlddkyrkqladrerellpiygqislqfadlhdr
ssrmvakgviskelewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswy
pasvdheddrqvatwieenyktlddklkglklesfa

Chain 'B':
Sequence, based on SEQRES records: (download)

>3tvuB (B:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepegtveikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3tvuB (B:)
lrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffis
neliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpq
edeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylylt
segmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsray
hdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevytsnlqlgg
tqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptnde
tydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtv
enlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilanwrgfsgg
qrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvn
aragvlepegtveikfrreklldtmnrlddkyrelladrerellpiygqislqfadlhdr
ssrmvakgviskelewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswy
pasvdheddrqvatwieenyktlddklkgl

Chain 'C':
Sequence, based on SEQRES records: (download)

>3tvuC (C:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepegtveikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3tvuC (C:)
pkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffisneliedengelteve
repganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpqedeffnkvteyarkr
gipriylaansgarigmaeeivplfqvawndaanpdkgfqylyltsegmetlkkfdkens
vltertvingeerfviktiigsedglgveclrgsgliagatsrayhdiftitlvtcrsvg
igaylvrlgqraiqvegqpiiltgasalnkvlgrevytsnlqlggtqimynngvshltav
ddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptndetydvrwmiegretes
gfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtvenlipadpanpnsae
tliqqagqvwfpnsafktaqaindfnngeqlpmmilanwrgfsggqrdmfnevlkygsfi
vdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvnaragvlepegtveik
frreklldtmnrlddkyrelrsqladrerellpiygqislqfadlhdrssrmvakgvisk
elewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswypasvdheddrqv
atwieenyktlddklkglkle