SCOPe 2.07: Structural Classification of Proteins

PDB entry 3tv5

View 3tv5 on RCSB PDB site
Description: Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 1
Class: ligase
Keywords: carboxyltransferase, ligase
Deposited on 2011-09-19, released 2011-10-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-12-14, with a file datestamp of 2011-12-09.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.174
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: acetyl-coa carboxylase
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: ACC1, ABP2, FAS3, MTR7, YNR016C, N3175
Database cross-references and differences (RAF-indexed):
- Uniprot Q00955
  - engineered mutation (287)
  - engineered mutation (289)
  - engineered mutation (292)
  - engineered mutation (446-447)
  - engineered mutation (452)
  - engineered mutation (555)
  - engineered mutation (557)
  - engineered mutation (559)
Domains in SCOPe 2.07: d3tv5a1, d3tv5a2
Chain 'B':
Compound: acetyl-coa carboxylase
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: ACC1, ABP2, FAS3, MTR7, YNR016C, N3175
Database cross-references and differences (RAF-indexed):
- Uniprot Q00955
  - engineered mutation (287)
  - engineered mutation (289)
  - engineered mutation (292)
  - engineered mutation (446-447)
  - engineered mutation (452)
  - engineered mutation (555)
  - engineered mutation (557)
  - engineered mutation (559)
Domains in SCOPe 2.07: d3tv5b1, d3tv5b2
Chain 'C':
Compound: acetyl-coa carboxylase
Species: Saccharomyces cerevisiae S288c [TaxId:559292]
Gene: ACC1, ABP2, FAS3, MTR7, YNR016C, N3175
Database cross-references and differences (RAF-indexed):
- Uniprot Q00955
  - engineered mutation (287)
  - engineered mutation (289)
  - engineered mutation (292)
  - engineered mutation (446-447)
  - engineered mutation (452)
  - engineered mutation (555)
  - engineered mutation (557)
  - engineered mutation (559)
Domains in SCOPe 2.07: d3tv5c1, d3tv5c2
Heterogens: RCP, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3tv5A (A:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepegtveikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3tv5A (A:)
lrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffis
neliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpq
edeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylylt
segmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsray
hdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevytsnlqlgg
tqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptnde
tydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtv
enlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilanwrgfsgg
qrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvn
aragvlepegtveikfrreklldtmnrlddkyrkqladrerellpiygqislqfadlhdr
ssrmvakgviskelewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswy
pasvdheddrqvatwieenyktlddklkglklesfa

Chain 'B':
Sequence, based on SEQRES records: (download)

>3tv5B (B:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepegtveikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3tv5B (B:)
lrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffis
neliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpq
edeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylylt
segmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsray
hdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevytsnlqlgg
tqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptnde
tydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtv
enlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilanwrgfsgg
qrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvn
aragvlepegtveikfrreklldtmnrlddkyrelladrerellpiygqislqfadlhdr
ssrmvakgviskelewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswy
pasvdheddrqvatwieenyktlddklkgl

Chain 'C':
Sequence, based on SEQRES records: (download)

>3tv5C (C:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgasalnkvlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqqagqvwfpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepegtveikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3tv5C (C:)
wlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffisneliedengelt
everepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpqedeffnkvteya
rkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylyltsegmetlkkfdk
ensvltertvingeerfviktiigsedglgveclrgsgliagatsrayhdiftitlvtcr
svgigaylvrlgqraiqvegqpiiltgasalnkvlgrevytsnlqlggtqimynngvshl
tavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptndetydvrwmiegre
tesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtvenlipadpanpn
saetliqqagqvwfpnsafktaqaindfnngeqlpmmilanwrgfsggqrdmfnevlkyg
sfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvnaragvlepegtv
eikfrreklldtmnrlddkyrelrsqladrerellpiygqislqfadlhdrssrmvakgv
iskelewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswypasvdhedd
rqvatwieenyktlddklkglkle