PDB entry 3tu5

View 3tu5 on RCSB PDB site
Description: Actin complex with Gelsolin Segment 1 fused to Cobl segment
Class: structural protein/actin-binding protein
Keywords: Unusual hairpin conformation in the D-loop, STRUCTURAL PROTEIN-ACTIN-BINDING PROTEIN complex
Deposited on 2011-09-15, released 2012-09-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-10-10, with a file datestamp of 2012-10-05.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.167
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tu5a1, d3tu5a2
  • Chain 'B':
    Compound: Gelsolin, Protein cordon-bleu, Thymosin beta-4
    Species: HOMO SAPIENS, MUS MUSCULUS [TaxId:9606, 10090]
    Gene: GSN, Cobl, Kiaa0633, TB4X, THYB4, TMSB4, TMSB4X
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06396 (Start-140)
      • expression tag (18)
    • Uniprot Q5NBX1 (141-End)
      • conflict (145)
    • Uniprot P62328
    Domains in SCOPe 2.06: d3tu5b1, d3tu5b2
  • Heterogens: CA, ATP, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3tu5A (A:)
    mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
    qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
    mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
    dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
    syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
    msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
    kqeydeagpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >3tu5A (A:)
    ettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrg
    iltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqim
    fetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagr
    dltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelp
    dgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggt
    tmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyd
    eagpsivhrk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3tu5B (B:)
    mnhkvhhhhhhiegrhmgsvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgd
    ayvilktvqlrngnlqydlhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfe
    satflgyfksglkykkggvasklrkvaeqtsegrpkkpsyveaesersallaairghsgt
    lslrkvsslaseelqsfrnaalgapgldkpqqedlglppppalppppapapqapsasvtv
    srfstgtpsnsvnarqalmdairsgtgaarlrktetqeknplpsketieqekqages
    

    Sequence, based on observed residues (ATOM records): (download)
    >3tu5B (B:)
    svvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
    lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
    vasklrkvaeqt