PDB entry 3tu0

View 3tu0 on RCSB PDB site
Description: Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium
Class: transport protein
Keywords: LeuT-fold, sodium-dependent amino acid transporter, plasma membrane, TRANSPORT PROTEIN
Deposited on 2011-09-15, released 2012-01-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-02-01, with a file datestamp of 2012-01-27.
Experiment type: XRAY
Resolution: 2.99 Å
R-factor: 0.221
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leucine transporter LeuT
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: snf, aq_2077
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67854 (Start-512)
      • engineered mutation (287)
      • engineered mutation (353-354)
      • expression tag (513-514)
    Domains in SCOPe 2.05: d3tu0a_
  • Heterogens: NA, ALA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tu0A (A:)
mevkrehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmw
iewamgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfai
kflvglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinv
silirgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkd
pgvwiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlneaaevilggsisip
aavaffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffaglvasiaim
qpmiafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffgltel
iiffwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeeth
wtvwitrfyiiglflfltflvflaerrrnhesagtlvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >3tu0A (A:)
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpeppptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirg
iskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwia
avgqifftlslgfgaiityasyvrkdqdivlsgltaatlneaaevilggsisipaavaff
gvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffaglvasiaimqpmiaf
ledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwi
fgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwit
rfyiiglflfltflvflaerrrnhesagt