PDB entry 3tsk
View 3tsk on RCSB PDB site
Description: Human MMP12 in complex with L-glutamate motif inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: pseudo dipeptides, potent inhibitors, metzincin, Zinc metalloprotease, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2011-09-13, released
2012-06-20
The last revision prior to the SCOPe 2.05 freeze date was dated
2012-10-17, with a file datestamp of
2012-10-12.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.166
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: HME, MMP12
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (1-158)
- initiating methionine (0)
- engineered mutation (66)
Domains in SCOPe 2.05: d3tska_ - Heterogens: ZN, CA, QEG, HOH