PDB entry 3tnq

View 3tnq on RCSB PDB site
Description: Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Class: transferase
Keywords: PKA RIIb tetrameric holoenzyme, TRANSFERASE
Deposited on 2011-09-01, released 2012-02-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-09-26, with a file datestamp of 2012-09-21.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.234
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase type II-beta regulatory subunit
    Species: Mus musculus [TaxId:10090]
    Gene: Prkar2b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31324
      • engineered mutation (229)
  • Chain 'B':
    Compound: Protein kinase, cAMP-dependent, catalytic, alpha
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Prkaca, rCG_51506
    Database cross-references and differences (RAF-indexed):
    • Uniprot A1L1M0 (Start-349)
      • conflict (41)
      • conflict (123)
    Domains in SCOPe 2.06: d3tnqb_
  • Heterogens: MG, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tnqB (B:)
gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
qvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffa
dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfatt
dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

    Sequence, based on observed residues (ATOM records): (download) 
    >3tnqB (B:)
eflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamkildk
qkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlrrig
rfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkgrtw
tlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsgkvr
fpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveapfip
kfkgpgdtsnfddyeeeeirvsinekcgkeftef