PDB entry 3tnp
View 3tnp on RCSB PDB site
Description: Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Class: transferase
Keywords: PKA RIIb tetrameric holoenzyme, TRANSFERASE
Deposited on
2011-09-01, released
2012-02-01
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-02-27, with a file datestamp of
2013-02-22.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.226
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'B':
Compound: cAMP-dependent protein kinase type II-beta regulatory subunit
Species: Mus musculus [TaxId:10090]
Gene: Prkar2b
Database cross-references and differences (RAF-indexed):
- Uniprot P31324
- engineered mutation (229)
- Chain 'C':
Compound: cAMP-dependent protein kinase catalytic subunit alpha
Species: Mus musculus [TaxId:10090]
Gene: Pkaca, Prkaca, rCG_51506
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3tnpc_ - Chain 'E':
Compound: cAMP-dependent protein kinase type II-beta regulatory subunit
Species: Mus musculus [TaxId:10090]
Gene: Prkar2b
Database cross-references and differences (RAF-indexed):
- Uniprot P31324
- engineered mutation (229)
- Chain 'F':
Compound: cAMP-dependent protein kinase catalytic subunit alpha
Species: Mus musculus [TaxId:10090]
Gene: Pkaca, Prkaca, rCG_51506
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3tnpf_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3tnpC (C:)
gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
qvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffa
dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfatt
dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef
Sequence, based on observed residues (ATOM records): (download)
>3tnpC (C:)
svkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkg
rtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfkgpgdtsnfddyeeeeirvsinekcgkeftef
- Chain 'E':
No sequence available.
- Chain 'F':
Sequence, based on SEQRES records: (download)
>3tnpF (F:)
gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
qvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffa
dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfatt
dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef
Sequence, based on observed residues (ATOM records): (download)
>3tnpF (F:)
svkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkg
rtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfkgpgdtsnfddyeeeeirvsinekcgkeftef