PDB entry 3tj5

View 3tj5 on RCSB PDB site
Description: human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
Class: protein binding/toxin
Keywords: cytoskeleton, epidemic typhus, sca4, spotted fever, ALPHA-HELIX BUNDLE DOMAIN, PROTEIN-PROTEIN INTERACTIONS, CELL ADHESION, CYTOSOL, FOCAL ADHESION, protein binding-toxin complex
Deposited on 2011-08-23, released 2011-09-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vinculin
    Species: Homo sapiens [TaxId:9606]
    Gene: VCL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3tj5a1, d3tj5a2
  • Chain 'B':
    Compound: Antigenic heat-stable 120 kDa protein
    Species: Rickettsia rickettsii str. Iowa [TaxId:452659]
    Gene: RrIowa_0797, sca4
    Database cross-references and differences (RAF-indexed):
    • Uniprot B0BXR4 (4-26)
      • expression tag (0-3)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tj5A (A:)
mpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgke
tvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgts
dllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqq
elthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsae
ineiirvlqltswde

    Sequence, based on observed residues (ATOM records): (download) 
    >3tj5A (A:)
pvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgket
vqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgtsd
llltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqqe
lthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsaei
neiirvlqltswde

  • Chain 'B':
    No sequence available.